Home > Search Results: Diabetic nephropathy
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Results overview: Found 6 records in 0.02 seconds.
Articles, 5 records found
Research literature, 1 records found
Articles 5 records found  
1.
23 p, 3.3 MB Enhanced Cardiorenal Protective Effects of Combining SGLT2 Inhibition, Endothelin Receptor Antagonism and RAS Blockade in Type 2 Diabetic Mice / Vergara, Ander (Hospital Universitari Vall d'Hebron) ; Jacobs-Cachá, Conxita (Hospital Universitari Vall d'Hebron. Institut de Recerca) ; Llorens-Cebria, Carmen (Hospital Universitari Vall d'Hebron. Institut de Recerca) ; Ortiz, Alberto (Universidad Autónoma de Madrid) ; Martinez-Diaz, Irene (Hospital Universitari Vall d'Hebron. Institut de Recerca) ; Martos, Nerea (Hospital Universitari Vall d'Hebron. Institut de Recerca) ; Dominguez-Báez, Pamela (Hospital Universitari Vall d'Hebron. Institut de Recerca) ; Van den Bosch, Mireia Molina (Hospital Universitari Vall d'Hebron. Institut de Recerca) ; Bermejo García, Sheila (Hospital Universitari Vall d'Hebron) ; Pieper, Michael Paul (Boehringer Ingelheim Pharma GmbH (Alemanya)) ; Benito, Begoña (Universitat Autònoma de Barcelona. Departament de Medicina) ; Soler, Maria Jose (Hospital Universitari Vall d'Hebron)
Treatments with sodium-glucose 2 cotransporter inhibitors (SGLT2i) or endothelin receptor antagonists (ERA) have shown cardiorenal protective effects. The present study aimed to evaluate the cardiorenal beneficial effects of the combination of SGLT2i and ERA on top of renin-angiotensin system (RAS) blockade. [...]
2022 - 10.3390/ijms232112823
International journal of molecular sciences, Vol. 23 (october 2022)  
Detailed record - Creative Commons
2.
1.4 MB The contribution of genetic variants of SLC2A1 gene in T2DM and T2DM-nephropathy : association study and meta-analysis / Stefanidis, I. (University of Thessaly School of Medicine. Department of Nephrology) ; Tziastoudi, M. (University of Thessaly School of Medicine. Department of Biomathematics) ; Tsironi, E. E. (University of Thessaly School of Medicine. Department of Ophthalmology) ; Dardiotis, Efthimios (University of Thessaly School of Medicine. Department of Neurology) ; Tachmitzi, S. V. (University of Thessaly School of Medicine. Department of Ophthalmology) ; Fotiadou, A. (University of Thessaly School of Medicine. Department of Ophthalmology) ; Pissas, G. (University of Thessaly School of Medicine. Department of Nephrology) ; Kytoudis, K. (University of Thessaly School of Medicine. Department of Nephrology) ; Sounidaki, M. (University of Thessaly School of Medicine. Department of Nephrology) ; Ampatzis, G. (University of Thessaly School of Medicine. Department of Nephrology) ; Mertens, P. R. (University of Magdeburg, Magdeburg. Department of Nephrology) ; Liakopoulos, V. (University of Thessaly School of Medicine. Department of Nephrology) ; Eleftheriadis, T. (University of Thessaly School of Medicine. Department of Nephrology) ; Hadjigeorgiou, Georgios M (University of Thessaly School of Medicine. Department of Neurology) ; Santos, Mauro (Universitat Autònoma de Barcelona. Departament de Genètica i de Microbiologia) ; Zintzaras, E. (Tufts University School of Medicine. The Institute for Clinical Research and Health Policy Studies)
An association study was conducted to investigate the relation between 14 variants of glucose transporter 1 gene (SLC2A1) and the risk of type 2 diabetes (T2DM) leading to nephropathy. We also performed a meta-analysis of 11 studies investigating association between diabetic nephropathy (DN) and SLC2A1 variants. [...]
2018 - 10.1080/0886022X.2018.1496931
Renal Failure, Vol. 40, Num. 1 (October 2018) , p. 561-576  
Detailed record - Creative Commons
3.
4 p, 390.4 KB Sodium-glucose cotransporter inhibitors : beyond glycaemic control / Vergara, Ander (Hospital Universitari Vall d'Hebron. Institut de Recerca) ; Jacobs-Cachá, Conxita (Hospital Universitari Vall d'Hebron. Institut de Recerca) ; Soler, María José (Hospital Universitari Vall d'Hebron. Institut de Recerca) ; Universitat Autònoma de Barcelona ; Hospital Universitari Vall d'Hebron
Diabetes increases the risk of adverse cardiovascular and renal events. Recently, sodium-glucose co-transporter 2 (SGLT2) inhibitors have been demonstrated to reduce cardiovascular complications and slow diabetic kidney disease progression in patients with type 2 diabetes. [...]
2019 - 10.1093/ckj/sfz019
Clinical Kidney Journal, Vol. 12 (march 2019) , p. 322-325  
Detailed record - Creative Commons
4.
12 p, 363.1 KB Renal Biopsy in Type 2 Diabetic Patients / Espinel Garuz, Eugenia (Hospital Universitari Vall d'Hebron) ; Agraz Pamplona, Irene (Hospital Universitari Vall d'Hebron) ; Ibernon, Meritxell (Hospital Universitari Vall d'Hebron) ; Ramos Terrades, Natalia (Hospital Universitari Vall d'Hebron) ; Fort Ros, Joan (Hospital Universitari Vall d'Hebron) ; Seron, Daniel (Hospital Universitari Vall d'Hebron) ; Universitat Autònoma de Barcelona
The majority of diabetic patients with renal involvement are not biopsied. Studies evaluating histological findings in renal biopsies performed in diabetic patients have shown that approximately one third of the cases will show pure diabetic nephropathy, one third a non-diabetic condition and another third will show diabetic nephropathy with a superimposed disease. [...]
2015 - 10.3390/jcm4050998
Journal of clinical medicine, Vol. 4 (may 2015) , p. 998-1009  
Detailed record - Creative Commons
5.
9 p, 343.2 KB Chronic kidney disease in the type 2 diabetic patients: prevalence and associated variables in a random sample of 2642 patients of a Mediterranean area / Coll-de-Tuero, Gabriel (Universitat de Girona) ; Mata Cases, Manel (Institut Català de la Salut) ; Rodriguez Poncelas, Antonio (I. A. S. (Salt, Girona)) ; Pepió, Josep M. (Institut Universitari d'Investigació en Atenció Primària (Tortosa, Catalunya)) ; Roura Olmeda, Pilar (Universitat Autònoma de Barcelona) ; Benito, Belén (Institut Català de la Salut) ; Franch-Nadal, Josep (Institut Català de la Salut) ; Sáez i Zafra, Marc (Universitat de Girona)
Background: Kidney disease is associated with an increased total mortality and cardiovascular morbimortality in the general population and in patients with Type 2 diabetes. The aim of this study is to determine the prevalence of kidney disease and different types of renal disease in patients with type 2 diabetes (T2DM). [...]
2012 - 10.1186/1471-2369-13-87
BMC Nephrology, Vol. 13, Núm. 87 (August 2012) , p. 1-9
3 documents
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Research literature 1 records found  
1.
158 p, 3.2 MB Caracterització de la nova línia nod.Ace2-/-: estudi de l'aparició de diabetis i la progressió de la nefropatia diabètica / Roca Ho, Heleia ; Pascual, Julio, (Pascual Santos) dir. ; Soler Romeo, MªJosé, dir. ; Riera Oliva, Marta, dir. ; Bosch i Merino, Assumpció ; Universitat Autònoma de Barcelona. Departament de Bioquímica i de Biologia Molecular
L'enzim convertidor d'angiotensina (ECA) promou la formació de l'angiotensina II (Ang-II). Contràriament, l'ECA2, una monocarboxipeptidasa que presenta un 40% d'homologia amb l'ECA, degrada l'Ang-II (accions vasoconstrictores) a angiotensina 1-7 (Ang-(1-7) (accions vasodilatadores). [...]
Angiotensin converting enzyme (ACE) promotes angiotensin II (Ang II) formation. Conversely, ACE2, a monocarboxipeptidase that shares 40% homology with ACE, degrades promotes angiotensin 1-7 (Ang- (1-7) (vasodilator actions) formation from Ang-II (vasoconstrictor actions). [...]
[Barcelona] : Universitat Autònoma de Barcelona, 2015  
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