Web of Science: 1 citations, Scopus: 1 citations, Google Scholar: citations,
Analysis of the genetic diversity and mRNA expression level in porcine reproductive and respiratory syndrome virus vaccinated pigs that developed short or long viremias after challenge
Cortey, Martí
Arocena, Gaston (Universitat Autònoma de Barcelona. Departament de Sanitat i Anatomia Animals)
Ait-Ali, Tahar (Universitat Autònoma de Barcelona. Departament de Sanitat i Anatomia Animals)
Vidal, Anna (Universitat Autònoma de Barcelona. Departament de Sanitat i Anatomia Animals)
Li, Yanli (Universitat Autònoma de Barcelona. Departament de Sanitat i Anatomia Animals)
Martín-Valls, Gerard (Universitat Autònoma de Barcelona. Departament de Sanitat i Anatomia Animals)
Wilson, Alison D. (Midlothian)
Archibald, Allan L. (Midlothian)
Mateu de Antonio, Enric (Universitat Autònoma de Barcelona. Departament de Sanitat i Anatomia Animals)
Darwich, Laila (Fundació Centre de Recerca en Sanitat Animal)

Date: 2018
Abstract: Porcine reproductive and respiratory syndrome virus (PRRSv) infection alters the host's cellular and humoral immune response. Immunity against PRRSv is multigenic and vary between individuals. The aim of the present study was to compare several genes that encode for molecules involved in the immune response between two groups of vaccinated pigs that experienced short or long viremic periods after PRRSv challenge. These analyses include the sequencing of four SLA Class I, two Class II allele groups, and CD163, plus the analysis by quantitative realtime qRT-PCR of the constitutive expression of TLR2, TLR3, TLR4, TLR7, TLR8 and TLR9 mRNA and other molecules in peripheral blood mononuclear cells.
Rights: Aquest document està subjecte a una llicència d'ús Creative Commons. Es permet la reproducció total o parcial, la distribució, la comunicació pública de l'obra i la creació d'obres derivades, fins i tot amb finalitats comercials, sempre i quan es reconegui l'autoria de l'obra original. Creative Commons
Language: Anglès.
Document: article ; recerca ; publishedVersion
Published in: Veterinary research, Vol. 49 (february 2018) , ISSN 1297-9716

PMID: 29448955
DOI: 10.1186/s13567-018-0514-1


6 p, 950.8 KB

The record appears in these collections:
Articles > Research articles
Articles > Published articles

 Record created 2018-03-06, last modified 2019-11-05



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