Nanoparticles for imaging, sensing, and therapeutic intervention
Bogart, Lara K. (University of Liverpool)
Pourroy, Genevieve (Institut de Physique et Chimie des Matériaux de Strasbourg)
Murphy, Catherine J. (University of Illinois at Urbana-Champaign)
Puntes, Víctor (Institut Català de Nanociència i Nanotecnologia)
Pellegrino, Teresa (Istituto Italiano di Tecnologia)
Rosenblum, Daniel (Tel Aviv University)
Peer, Dan (Tel Aviv University)
Lévy, Rapäel (University of Liverpool)

Date:	2014
Abstract:	Nanoparticles have the potential to contribute to new modalities in molecular imaging and sensing as well as in therapeutic interventions. In this Nano Focus article, we identify some of the current challenges and knowledge gaps that need to be confronted to accelerate the developments of various applications. Using specific examples, we journey from the characterization of these complex hybrid nanomaterials; continue with surface design and (bio)physicochemical properties, their fate in biological media and cells, and their potential for cancer treatment; and finally reflect on the role of animal models to predict their behavior in humans.
Rights:	Aquest document està subjecte a una llicència d'ús Creative Commons. Es permet la reproducció total o parcial, la distribució, la comunicació pública de l'obra i la creació d'obres derivades, fins i tot amb finalitats comercials, sempre i quan es reconegui l'autoria de l'obra original.
Language:	Anglès
Document:	Article ; recerca ; Versió publicada
Subject:	Animal model ; Biological media ; Hybrid nanomaterials ; Knowledge gaps ; New modality ; Physicochemical property ; Surface design ; Therapeutic intervention ; Animals ; Biocompatible Materials ; Humans ; Molecular Imaging ; Nanomedicine ; Nanoparticles
Published in:	ACS nano, Vol. 8, Núm. 4 (April 2014) , p. 3107-3122, ISSN 1936-086X

DOI: 10.1021/nn500962q
PMID: 24641589

16 p, 4.8 MB

The record appears in these collections:
Research literature > UAB research groups literature > Research Centres and Groups (research output) > Experimental sciences > Catalan Institute of Nanoscience and Nanotechnology (ICN2)
Articles > Research articles
Articles > Published articles