Integrated bimodal waveguide interferometric biosensor for label-free analysis
Zinoviev, K. E. (Institut de Microelectrònica de Barcelona)
González-Guerrero, Ana Belén (Institut Català de Nanociència i Nanotecnologia)
Dominguez, Carlos (Institut de Microelectrònica de Barcelona)
Lechuga, Laura M (Institut Català de Nanociència i Nanotecnologia)

Date:	2011
Abstract:	The performance of an interferometric device based on integrated Bimodal Waveguides (BiMW) for sensing is demonstrated. The sensors are fabricated using standard silicon technology and can achieve a detection limit of 2. 5 · 10 RIU for homogeneous sensing, rendering in a very high sensitive device. The applicability of the bimodal waveguide interferometer as label-free biosensor has been demonstrated by the real-time monitoring of the biomolecular interaction of BSA and antiBSA. Due to their simplicity, the interferometric devices could be further integrated in complete lab-on-a-chip platforms for point-of-care diagnostics showing them as a powerful instrument for biochemical analysis.
Note:	Altres ajuts: MINETUR/TSI-020301-2008-11
Rights:	Tots els drets reservats.
Language:	Anglès
Document:	Article ; recerca ; Versió acceptada per publicar
Subject:	Bimodal waveguide ; Evanescent wave detection ; Integrated optics ; Optical biosensors ; Waveguides
Published in:	Journal of lightwave technology, Vol. 29, Issue 13 (July 2011) , p. 1926-1930, ISSN 0733-8724

DOI: 10.1109/JLT.2011.2150734

Postprint 7 p, 288.5 KB

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Research literature > UAB research groups literature > Research Centres and Groups (research output) > Experimental sciences > Catalan Institute of Nanoscience and Nanotechnology (ICN2)
Articles > Research articles
Articles > Published articles