Google Scholar: citations
Flexible graphene transistors for recording cell action potentials
Blaschke, Benno M. (Technische Universität München. Walter Schottky Institut. Physik-Department)
Lottner, Martin (Technische Universität München. Walter Schottky Institut. Physik-Department)
Drieschner, Simon (Technische Universität München. Walter Schottky Institut. Physik-Department)
Bonaccini Calia, Andrea (Institut Català de Nanociència i Nanotecnologia)
Stoiber, Karolina (Technische Universität München. Walter Schottky Institut. Physik-Department)
Rousseau, Lionel (University Paris EST. École Supérieure d'Ingénieurs en Électrotechnique et Électronique)
Lissourges, Gaëlle (University Paris EST. École Supérieure d'Ingénieurs en Électrotechnique et Électronique)
Garrido Ariza, José A. (Institut Català de Nanociència i Nanotecnologia)

Date: 2016
Abstract: Graphene solution-gated field-effect transistors (SGFETs) are a promising platform for the recording of cell action potentials due to the intrinsic high signal amplification of graphene transistors. In addition, graphene technology fulfills important key requirements for in-vivo applications, such as biocompability, mechanical flexibility, as well as ease of high density integration. In this paper we demonstrate the fabrication of flexible arrays of graphene SGFETs on polyimide, a biocompatible polymeric substrate. We investigate the transistor's transconductance and intrinsic electronic noise which are key parameters for the device sensitivity, confirming that the obtained values are comparable to those of rigid graphene SGFETs. Furthermore, we show that the devices do not degrade during repeated bending and the transconductance, governed by the electronic properties of graphene, is unaffected by bending. After cell culture, we demonstrate the recording of cell action potentials from cardiomyocyte-like cells with a high signal-to-noise ratio that is higher or comparable to competing state of the art technologies. Our results highlight the great capabilities of flexible graphene SGFETs in bioelectronics, providing a solid foundation for in-vivo experiments and, eventually, for graphene-based neuroprosthetics.
Rights: Tots els drets reservats.
Language: Anglès.
Document: article ; recerca ; acceptedVersion
Subject: Bioelectronics ; Biosensors ; Flexible electronics ; Graphene
Published in: 2D Materials, Vol. 3, issue 2 (June 2016) , p. 25007, ISSN 2053-1583

DOI: 10.1088/2053-1583/3/2/025007


Postprint
12 p, 8.3 MB

The record appears in these collections:
Research literature > UAB research groups literature > Research Centres and Groups (scientific output) > Experimental sciences > Catalan Institute of Nanoscience and Nanotechnology (ICN2)
Articles > Research articles
Articles > Published articles

 Record created 2019-07-30, last modified 2019-10-04



   Favorit i Compartir