Tolerogenic dendritic cells as a cell therapy to prevent chronic rejection in kidney transplantation
Molina Molina, Elisa
Álvarez Pérez, Iñaki, dir. (Universitat Autònoma de Barcelona. Departament de Biologia Cel·lular, de Fisiologia i d'Immunologia)
Universitat Autònoma de Barcelona. Facultat de Biociències

Date:	2019
Abstract:	Kidney transplantation (KT) is nowadays a routine procedure for people with end-stage renal disease. Treatment with immunosuppressive (IS) drugs has significantly decreased acute rejection rates. However, rates of long-term kidney loss have remained rather constant over the last decades due to the persistence of chronic allograft injury. Moreover, the lack of specificity of IS drugs renders the recipient susceptible to infections and cancer in the long-term. In this sense, Tolerogenic Dendritic Cell (TolDC)-based therapy represents an innovative and promising approach to achieve kidney transplant success through the induction of immune tolerance.
Rights:	Aquest document està subjecte a una llicència d'ús Creative Commons. Es permet la reproducció total o parcial i la comunicació pública de l'obra, sempre que no sigui amb finalitats comercials, i sempre que es reconegui l'autoria de l'obra original. No es permet la creació d'obres derivades.
Language:	Anglès
Studies:	Ciències Biomèdiques [2501230]
Study plan:	Grau en Ciències Biomèdiques [832]
Document:	Treball final de grau ; Text
Subject:	Chronic rejection ; Kidney transplantation ; Iimmune tolerance ; Dendritic cells ; Tolerogenic dendritic cells

1 p, 1.7 MB

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Research literature > Bachelor's degree final project > Biosciences Faculty