Diagnostic accuracy of non-melanocytic pink flat skin lesions on the legs : Dermoscopic and reflectance confocal microscopy evaluation
Gómez Martín, Ignacio (Hospital del Mar (Barcelona, Catalunya))
Moreno Fernández, Sara (Hospital del Mar (Barcelona, Catalunya))
Duran-Jordà, Xavier (Institut Hospital del Mar d'Investigacions Mèdiques)
Pujol Vallverdú, Ramón M.. (Universitat Autònoma de Barcelona. Departament de Medicina)
Segura, Sonia (Hospital del Mar (Barcelona, Catalunya))

Data:	2018
Resum:	Pink flat skin lesions on the legs in elderly people represent a diagnostic challenge due to the paucity of clinical and dermoscopic evidence. A prospective study of 114 pink flat lesions on the legs of 85 elderly patients was performed to describe the utility of reflectance confocal microscopy in this clinical context. Evaluation of clinical, dermoscopic and confocal parameters and calculation of diagnostic accuracy/sensi-tivity/specificity for non-melanoma skin cancer diagnosis of each technique were carried out. Thirty-four benign and 80 malignant neoplasms were analysed. A correct clinical diagnosis was established in 49. 1% of cases (sensitivity 68. 7%, specificity 73. 5%). Dermoscopy achieved 59. 6% correct diagnosis (sensiti-vity 85%, specificity 67. 6%) and confocal microscopy evaluation after clinical and dermoscopic evaluation rendered a correct diagnosis in 85. 1% of cases (sensi-tivity 97. 5%, specificity 88. 2%). Confocal microscopy may improve diagnostic accuracy, sensitivity and specificity as a secondary evaluation after dermoscopy. A diagnostic confocal algorithm for pink flat lesions on the legs is proposed.
Ajuts:	Instituto de Salud Carlos III RD09-0076-00036 Instituto de Salud Carlos III PT13-0010-0005
Drets:	Aquest document està subjecte a una llicència d'ús Creative Commons. Es permet la reproducció total o parcial, la distribució, la comunicació pública de l'obra i la creació d'obres derivades, sempre que no sigui amb finalitats comercials, i sempre que es reconegui l'autoria de l'obra original.
Llengua:	Anglès
Document:	Article ; recerca ; Versió publicada
Matèria:	Dermoscopy ; Reflectance confocal microscopy ; Histopathology ; Basal cell carcinoma ; Bowen's disease ; Venous stasis dermatitis
Publicat a:	Acta dermato-venereologica, Vol. 99 Núm. 1 (january 2018) , p. 33-40, ISSN 1651-2057

DOI: 10.2340/00015555-3029
PMID: 30176037

8 p, 3.7 MB

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