From transformation to chronification of migraine : pathophysiological and clinical aspects
Torres-Ferrús, M. (Hospital Universitari Vall d'Hebron)
Ursitti, F. (Bambino Gesù Children's Hospital)
Alpuente, Alicia (Hospital Universitari Vall d'Hebron)
Brunello, F. (University Hospital of Padua. Juvenile Headache Centre, Department of Woman's and Child's Health)
Chiappino, D. (University of Rome. Department of Internal medicine, Sant'Andrea Hospital)
de Vries, T. (Erasmus University Medical Center. Division of Vascular Medicine and Pharmacology, Department of Internal Medicine)
Di Marco, S. (Policlinico Paolo Giaccone Hospital, University of Palermo. Department of Biomedicine Neuroscience and Advanced Diagnostics)
Ferlisi, S. (Policlinico Paolo Giaccone Hospital, University of Palermo. Department of Biomedicine Neuroscience and Advanced Diagnostics)
Guerritore, L. (University of Rome. Department of Internal medicine, Sant'Andrea Hospital)
Gonzalez-Garcia, N. (Hospital Clínico San Carlos (Madrid))
Gonzalez-Martinez, A. (Instituto de Investigación Hospital Universitario de la Princesa)
Khutorov, D. (Department of Clinical Neurology and Sleep Medicine, The Nikiforov Russian Center of Emergency and Radiation Medicine of EMERCOM of Russia)
Kritsilis, M. (Grevena General Hospital)
Kyrou, A. (Bern University Hospital)
Makeeva, T. (Headache Unit, Department of Neurology, Medical center "New Medical Technologies", Voronezh, Russia)
Minguez-Olaondo, A. (Hospital Quirónsalud Donostia)
Pilati, L. (Policlinico Paolo Giaccone Hospital, University of Palermo. Department of Biomedicine Neuroscience and Advanced Diagnostics)
Serrien, A. (University Hospitals Leuven (Bèlgica))
Tsurkalenko, O. (Dnipropetrovsk medical akademy MOH Ukraine. Department of Neurology and Neurosurgery)
Van den Abbeele, D. (Ghent University Hospital. (Bèlgica))
van Hoogstraten, W. S. (Erasmus University Medical Centre. Department of Neuroscience)
Lampl, Christian (Headache Medical Center Linz, Ordensklinikum Linz Barmherzige Schwestern)
Universitat Autònoma de Barcelona
Vall d'Hebron Institut de Recerca (VHIR)

Date:	2020
Abstract:	Chronic migraine is a neurological disorder characterized by 15 or more headache days per month of which at least 8 days show typical migraine features. The process that describes the development from episodic migraine into chronic migraine is commonly referred to as migraine transformation or chronification. Ample studies have attempted to identify factors associated with migraine transformation from different perspectives. Understanding CM as a pathological brain state with trigeminovascular participation where biological changes occur, we have completed a comprehensive review on the clinical, epidemiological, genetic, molecular, structural, functional, physiological and preclinical evidence available.
Rights:	Aquest document està subjecte a una llicència d'ús Creative Commons. Es permet la reproducció total o parcial, la distribució, la comunicació pública de l'obra i la creació d'obres derivades, fins i tot amb finalitats comercials, sempre i quan es reconegui l'autoria de l'obra original.
Language:	Anglès
Document:	Article ; recerca ; Versió publicada
Subject:	Chronic migraine ; Transformation ; Pathophysiology ; Risk factors ; Genetics ; Biomarker ; Neurophysiology ; Neuroimaging ; Animal models
Published in:	Journal of headache and pain, Vol. 21 (april 2020) , ISSN 1129-2377

DOI: 10.1186/s10194-020-01111-8
PMID: 32349653

12 p, 648.0 KB

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