Serum acute phase proteins in Dirofilaria immitis and Wolbachia seropositive cats
Silvestre-Ferreira, Ana C. (Universidade de Trás-os-Montes e Alto Douro. Department of Veterinary Sciences)
Vieira, Lisete (Universidade de Trás-os-Montes e Alto Douro. Department of Veterinary Sciences)
Vilhena, Hugo (Universidade Vasco da Gama. Department of Veterinary Medicine)
Cerón, José Joaquín (Universidad de Murcia. Interlab-UMU)
Tvarijonaviciute, Asta (Universitat Autònoma de Barcelona. Departament de Medicina i Cirurgia Animals)
Pastor Milán, Josep (Universitat Autònoma de Barcelona. Departament de Medicina i Cirurgia Animals)
Montoya Alonso, J. A. (Universidad de Las Palmas de Gran Canaria. Research Institute of Biomedical and Health Sciences)
Carretón, Elena (Universidad de Las Palmas de Gran Canaria. Research Institute of Biomedical and Health Sciences)

Date:	2017
Abstract:	Objectives The aim of this study was to characterise the response of acute phase proteins (APPs) in cats seropositive for Dirofilaria immitis and to its endosymbiont bacterium Wolbachia.
Abstract:	Methods The APPs serum amyloid A (SAA), haptoglobin (Hp) and ceruloplasmin (Cp) were measured in 25 seropositive cats and in 16 healthy seronegative cats.
Abstract:	Results SAA and Cp concentrations were significantly higher in animals with D immitis seropositivity that exhibited clinical signs related to the disease, and Hp was elevated in all D immitis-seropositive animals. There was no significant correlation between APPs and D immitis or Wolbachia species antibody titres.
Abstract:	Conclusions and relevance An association between feline seropositivity to D immitis and APP response was demonstrated. Increases in serum SAA and Cp concentrations were related to D immitis-associated clinical signs, whereas Hp increased in all seropositive animals.
Rights:	Aquest document està subjecte a una llicència d'ús Creative Commons. Es permet la reproducció total o parcial, la distribució, la comunicació pública de l'obra i la creació d'obres derivades, fins i tot amb finalitats comercials, sempre i quan es reconegui l'autoria de l'obra original.
Language:	Anglès
Document:	Article ; recerca ; Versió publicada
Subject:	Gats ; Malalties ; Nematodes ; Paràsits ; Dirofilariasi felina
Published in:	Journal of feline medicine and surgery, Vol. 19 Núm. 6 (2017) , p. 693-696, ISSN 1532-2750

DOI: 10.1177/1098612X15625435
PMID: 26783021

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Research literature > UAB research groups literature > Research Centres and Groups (research output) > Health sciences and biosciences > Research group Wildlife Ecology & Health
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