Perioperative stress response in dogs undergoing elective surgery : variations in behavioural, neuroendocrine, immune and acute phase responses
Siracusa, Carlo (University of Pennsylvania. Department of Clinical Studies)
Manteca Vilanova, Xavier (Universitat Autònoma de Barcelona. Departament de Ciència Animal i dels Aliments)
Cerón, José Joaquín (Universidad de Murcia. Departamento de Medicina y Cirugía Animal)
Martínez-Subiela, Silvia (Universidad de Murcia. Departamento de Medicina y Cirugía Animal)
Cuenca Valera, Rafaela (Universitat Autònoma de Barcelona. Departament de Medicina i Cirurgia Animals)
Lavín González, Santiago (Universitat Autònoma de Barcelona. Departament de Medicina i Cirurgia Animals)
García Arnas, Félix (Universitat Autònoma de Barcelona. Departament de Medicina i Cirurgia Animals)
Pastor Milán, Josep (Universitat Autònoma de Barcelona. Departament de Medicina i Cirurgia Animals)

Date:	2008
Abstract:	The aim of this trial was to describe the behavioural, neuroendocrine, immune and acute phase stress responses in dogs undergoing elective surgery in normal, clinical practice conditions. Sixteen dogs were submitted to elective orchiectomy or ovariohysterectomy using a standardised surgical protocol. Each animal was confined to the Intensive Care Unit during pre- and post-surgery and perioperative behavioural, neuroendocrine, immune and acute phase responses were studied. Behavioural categories, cortisol, prolactin, white blood cell, C-reactive protein and haptoglobin variation were evaluated. Values at different times were compared with basal values shown by the dog in its usual environment. Communicative and explorative behaviours showed high occurrence pre-surgery and were inhibited post-surgery. Decreases in post-surgery activity, interactive behaviours and changes in waking/sleeping patterns were observed. The most sensitive marker of psychological stress, cortisol, in comparison with basal values, showed a significant increase both during pre- and post-surgery confinement in the ICU cage. Prolactin values were characterised by a significant decrease early into the post-surgery period. The immune response was characterised by long-term neutrophilia and monocytosis, but by short-term lymphopaenia and eosinopaenia, limited to the early post-operative period. With regard to the acute phase response, both C-reactive protein and haptoglobin showed a long-term increase, post-surgery. Changes in behavioural, haematological and biochemical markers showed that perioperative stress represents a major challenge to dog welfare.
Rights:	Aquest document està subjecte a una llicència d'ús Creative Commons. Es permet la reproducció total o parcial, la distribució, la comunicació pública de l'obra i la creació d'obres derivades, fins i tot amb finalitats comercials, sempre i quan es reconegui l'autoria de l'obra original.
Language:	Anglès
Document:	Article ; recerca ; Versió publicada
Subject:	Gossos ; Cirurgia ; Efectes de l'estrès sobre ; Animal welfare ; Behavioural response ; Dog ; Immune response ; Neuroendocrine response ; Perioperative stress
Published in:	Animal Welfare, Vol. 17 Núm. 3 (2008) , p. 259-273, ISSN 2054-1538

15 p, 608.5 KB

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Research literature > UAB research groups literature > Research Centres and Groups (research output) > Health sciences and biosciences > Research group Wildlife Ecology & Health
Articles > Research articles
Articles > Published articles