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Página principal > Artículos > Artículos publicados > Multiplexed neural sensor array of graphene solution-gated field-effect transistors |
Fecha: | 2020 |
Resumen: | Electrocorticography (ECoG) is a well-established technique to monitor electrophysiological activity from the surface of the brain and has proved crucial for the current generation of neural prostheses and brain-computer interfaces. However, existing ECoG technologies still fail to provide the resolution necessary to accurately map highly localized activity across large brain areas, due to the rapidly increasing size of connector footprint with sensor count. This work demonstrates the use of a flexible array of graphene solution-gated field-effect transistors (gSGFET), exploring the concept of multiplexed readout using an external switching matrix. This approach does not only allow for an increased sensor count, but due to the use of active sensing devices (i. e. transistors) over microelectrodes it makes additional buffer transistors redundant, which drastically eases the complexity of device fabrication on flexible substrates. The presented results pave the way for upscaling the gSGFET technology towards large-scale, high-density μECoG-arrays, eventually capable of resolving neural activity down to a single neuron level, while simultaneously mapping large brain regions. |
Ayudas: | European Commission 785219 European Commission 732032 Ministerio de Economía y Competitividad CTQ2015-65439-R Ministerio de Economía y Competitividad SEV-2017-0706 Ministerio de Ciencia e Innovación FIS2017-85787-R Agència de Gestió d'Ajuts Universitaris i de Recerca 2017/SGR-1426 |
Nota: | Altres ajuts: this work has made use of the Spanish ICTS Network MICRONANOFABS partially supported by MICINN and the ICTS 'NANBIOSIS', more specifically by the Micro-NanoTechnology Unit of the CIBER in Bioengineering, Biomaterials and Nanomedicine (CIBERBBN) at the IMB-CNM. |
Derechos: | Tots els drets reservats. |
Lengua: | Anglès |
Documento: | Article ; recerca ; Versió sotmesa a revisió |
Materia: | Multiplexed µECoGs ; Graphene solution-gated field-effect transistor ; Flexible probes ; Neurosensing |
Publicado en: | 2D materials, Vol. 7, issue 2 (April 2020) , art. 25046, ISSN 2053-1583 |
Preprint 13 p, 1.1 MB |