Real-time monitoring of fenitrothion in water samples using a silicon nanophotonic biosensor
Ramirez Priego, Patricia (Institut Català de Nanociència i Nanotecnologia)
Estévez, M. Carmen (Institut Català de Nanociència i Nanotecnologia)
Díaz-Luisravelo, Heriberto J. (Institut Català de Nanociència i Nanotecnologia)
Manclus, Juan (Universitat Politècnica de València. Centro de Investigación e Innovación en Bioingeniería)
Montoya, Angel (Universitat Politècnica de València. Centro de Investigación e Innovación en Bioingeniería)
Lechuga, Laura M (Institut Català de Nanociència i Nanotecnologia)

Date:	2021
Abstract:	Due to the large quantities of pesticides extensively used and their impact on the environment and human health, a prompt and reliable sensing technique could constitute an excellent tool for in-situ monitoring. With this aim, we have applied a highly sensitive photonic biosensor based on a bimodal waveguide interferometer (BiMW) for the rapid, label-free, and specific quantification of fenitrothion (FN) directly in tap water samples. After an optimization protocol, the biosensor achieved a limit of detection (LOD) of 0. 29 ng mL (1. 05 nM) and a half-maximal inhibitory concentration (IC) of 1. 71 ng mL (6. 09 nM) using a competitive immunoassay and employing diluted tap water. Moreover, the biosensor was successfully employed to determine FN concentration in blind tap water samples obtaining excellent recovery percentages with a time-to-result of only 20 min without any sample pre-treatment. The features of the biosensor suggest its potential application for real time, fast and sensitive screening of FN in water samples as an analytical tool for the monitoring of the water quality.
Grants:	Ministerio de Economía y Competitividad RTC-2017-6222-5 Ministerio de Economía y Competitividad SEV-2017-0706
Note:	Altres ajuts: the ICN2 is funded by the CERCA programme/Generalitat de Catalunya.
Rights:	Aquest document està subjecte a una llicència d'ús Creative Commons. Es permet la reproducció total o parcial, la distribució, i la comunicació pública de l'obra, sempre que no sigui amb finalitats comercials, i sempre que es reconegui l'autoria de l'obra original. No es permet la creació d'obres derivades.
Language:	Anglès
Document:	Article ; recerca ; Versió sotmesa a revisió
Subject:	Silicon photonics ; Optical sensor ; Environmental monitoring ; Pesticide ; Organophosphate ; Fenitrothion ; Label-free
Published in:	Analytica chimica acta, Vol. 1152 (Abril 2021) , art. 338276, ISSN 1873-4324

DOI: 10.1016/j.aca.2021.338276

Preprint 33 p, 971.2 KB

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Research literature > UAB research groups literature > Research Centres and Groups (research output) > Experimental sciences > Catalan Institute of Nanoscience and Nanotechnology (ICN2)
Articles > Research articles
Articles > Published articles