Home > Articles > Published articles > Real-time monitoring of fenitrothion in water samples using a silicon nanophotonic biosensor |
Date: | 2021 |
Abstract: | Due to the large quantities of pesticides extensively used and their impact on the environment and human health, a prompt and reliable sensing technique could constitute an excellent tool for in-situ monitoring. With this aim, we have applied a highly sensitive photonic biosensor based on a bimodal waveguide interferometer (BiMW) for the rapid, label-free, and specific quantification of fenitrothion (FN) directly in tap water samples. After an optimization protocol, the biosensor achieved a limit of detection (LOD) of 0. 29 ng mL (1. 05 nM) and a half-maximal inhibitory concentration (IC) of 1. 71 ng mL (6. 09 nM) using a competitive immunoassay and employing diluted tap water. Moreover, the biosensor was successfully employed to determine FN concentration in blind tap water samples obtaining excellent recovery percentages with a time-to-result of only 20 min without any sample pre-treatment. The features of the biosensor suggest its potential application for real time, fast and sensitive screening of FN in water samples as an analytical tool for the monitoring of the water quality. |
Grants: | Ministerio de Economía y Competitividad RTC-2017-6222-5 Ministerio de Economía y Competitividad SEV-2017-0706 |
Note: | Altres ajuts: the ICN2 is funded by the CERCA programme/Generalitat de Catalunya. |
Rights: | Aquest document està subjecte a una llicència d'ús Creative Commons. Es permet la reproducció total o parcial, la distribució, i la comunicació pública de l'obra, sempre que no sigui amb finalitats comercials, i sempre que es reconegui l'autoria de l'obra original. No es permet la creació d'obres derivades. |
Language: | Anglès |
Document: | Article ; recerca ; Versió sotmesa a revisió |
Subject: | Silicon photonics ; Optical sensor ; Environmental monitoring ; Pesticide ; Organophosphate ; Fenitrothion ; Label-free |
Published in: | Analytica chimica acta, Vol. 1152 (Abril 2021) , art. 338276, ISSN 1873-4324 |
Preprint 33 p, 971.2 KB |