International variation in the management of severe COVID-19 patients
Azoulay, Elie (Hôpital Saint-Louis (Paris, França))
De Waele, Jan J. (Universitair Ziekenhuis Gent)
Ferrer, Ricard (Hospital Universitari Vall d'Hebron)
Staudinger, T. (Medical University of Vienna)
Borkowska, M. (Universitair Ziekenhuis Gent)
Povoa, P. (New University of Lisbon)
Iliopoulou, Katerina (ICU Nurse Manager General Military Hospital)
Artigas Raventós, Antoni (Parc Taulí Hospital Universitari. Institut d'Investigació i Innovació Parc Taulí (I3PT))
Schaller, S. J. (Humboldt-Universität zu Berlin)
Shankar-Hari, M. (Guy's and St Thomas' NHS Foundation Trust)
Pellegrini, M. (University of Gothenburg)
Darmon, M. (Hôpital Saint-Louis. Paris University)
Kesecioglu, J. (Utrecht University)
Cecconi, Maurizio (Humanitas University)
Universitat Autònoma de Barcelona

Date:	2020
Abstract:	Background: There is little evidence to support the management of severe COVID-19 patients. Methods: To document this variation in practices, we performed an online survey (April 30-May 25, 2020) on behalf of the European Society of Intensive Care Medicine (ESICM). A case vignette was sent to ESICM members. Questions investigated practices for a previously healthy 39-year-old patient presenting with severe hypoxemia from COVID-19 infection. Results: A total of 1132 ICU specialists (response rate 20%) from 85 countries (12 regions) responded to the survey. The survey provides information on the heterogeneity in patient's management, more particularly regarding the timing of ICU admission, the first line oxygenation strategy, optimization of management, and ventilatory settings in case of refractory hypoxemia. Practices related to antibacterial, antiviral, and anti-inflammatory therapies are also investigated. Conclusions: There are important practice variations in the management of severe COVID-19 patients, including differences at regional and individual levels. Large outcome studies based on multinational registries are warranted.
Note:	COVID-19
Rights:	Aquest document està subjecte a una llicència d'ús Creative Commons. Es permet la reproducció total o parcial, la distribució, la comunicació pública de l'obra i la creació d'obres derivades, fins i tot amb finalitats comercials, sempre i quan es reconegui l'autoria de l'obra original.
Language:	Anglès
Document:	Article ; recerca ; Versió publicada
Subject:	Coronavirus ; Acute respiratory distress syndrome ; Viral infection ; Remdesi
Published in:	Critical care, Vol. 24 Núm. 1 (may 2020) , p. s13054-020-03194-w, ISSN 1466-609X

DOI: 10.1186/s13054-020-03194-w
PMID: 32758266

7 p, 1.4 MB

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Research literature > UAB research groups literature > Research Centres and Groups (research output) > Health sciences and biosciences > Parc Taulí Research and Innovation Institute (I3PT
Articles > Research articles
Articles > Published articles