Salmonella enterica from a soldier from the 1652 siege of Barcelona (Spain) supports historical transatlantic epidemic contacts
de-Dios, Toni (Institut de Biologia Evolutiva (UPF-CSIC) (Barcelona))
Carrión, Pablo (Institut de Biologia Evolutiva (UPF-CSIC) (Barcelona))
Olalde, Iñigo (Institut de Biologia Evolutiva (UPF-CSIC) (Barcelona))
Llovera, Laia (Institut de Biologia Evolutiva (UPF-CSIC) (Barcelona))
Lizano, Esther (Institut de Biologia Evolutiva (UPF-CSIC) (Barcelona))
Pàmies, Dídac (Antequem. Arqueologia Patrimoni Cultural)
Marquès i Bonet, Tomàs 1975- (Institut Català de Paleontologia Miquel Crusafont)
Balloux, François (University College London. UCL Genetics Institute)
van Dorp, Lucy (University College London. UCL Genetics Institute)
Lalueza-Fox, Carles (Institut de Biologia Evolutiva (UPF-CSIC) (Barcelona))

Date:	2021
Abstract:	Ancient pathogen genomics is an emerging field allowing reconstruction of past epidemics. The demise of post-contact American populations may, at least in part, have been caused by paratyphoid fever brought by Europeans. We retrieved genome-wide data from two Spanish soldiers who were besieging the city of Barcelona in 1652, during the Reapers' War. Their ancestry derived from the Basque region and Sardinia, respectively, (at that time, this island belonged to the Spanish kingdom). Despite the proposed plague epidemic, we could not find solid evidence for the presence of the causative plague agent in these individuals. However, we retrieved from one individual a substantial fraction of the Salmonella enterica serovar Paratyphi C lineage linked to paratyphoid fever in colonial period Mexico. Our results support a growing body of evidence that Paratyphi C enteric fever was more prevalent in Europe and the Americas in the past than it is today.
Grants:	Ministerio de Ciencia e Innovación PGC2018-0955931-B-100 European Commission 864203 Agencia Estatal de Investigación BFU2017-86471-P Ministerio de Ciencia e Innovación CEX2018-000792-M Agència de Gestió d'Ajuts Universitaris i de Recerca 2017/SGR-880
Rights:	Aquest document està subjecte a una llicència d'ús Creative Commons. Es permet la reproducció total o parcial, la distribució, la comunicació pública de l'obra i la creació d'obres derivades, fins i tot amb finalitats comercials, sempre i quan es reconegui l'autoria de l'obra original.
Language:	Anglès
Document:	Article ; recerca ; Versió publicada
Subject:	Biological sciences ; Genomic analysis ; Genomics ; Paleogenetics
Published in:	iScience, Vol. 24, Issue 9 (September 2021) , art. 103021, ISSN 2589-0042

DOI: 10.1016/j.isci.2021.103021
PMID: 34527890

19 p, 2.9 MB

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Research literature > UAB research groups literature > Research Centres and Groups (research output) > Experimental sciences > Institut Català de Paleontologia Miquel Crusafont (ICP)
Articles > Research articles
Articles > Published articles