Management Strategies for POSEIDON Groups 3 and 4
Haahr, Thor (The Fertility Clinic Skive, Skive Regional Hospital (Denmark))
Dosouto, Carlos (Institut d'Investigació Biomèdica Sant Pau)
Alviggi, Carlo (Istituto per L'Endocrinologia e L'Oncologia Sperimentale)
Esteves, Sandro C. (University of Campinas)
Humaidan, Peter (The Fertility Clinic Skive, Skive Regional Hospital)
Universitat Autònoma de Barcelona

Fecha:	2019
Resumen:	In the POSEIDON classification, patients belonging to groups 3 and 4 share the same common feature of a poor ovarian reserve which independently of age renders them at high risk of a poor reproductive outcome. Overall, POSEIDON groups 1-4 constitute approximately 47% of patients attending assisted reproductive technology (ART) treatment. With the increasing delay in childbearing, POSEIDON group 4 seems to increase in numbers now in some centers constituting more than 50% of the total POSEIDON population, whereas group 3 patients constitute approximately 10%. Both POSEIDON groups 3 and 4 patients require special attention as regards pre-treatment strategy, ovarian stimulation, adjuvant treatment, and ovulation trigger strategy in order to optimize the probability of having at least one euploid blastocyst for transfer. Although more evidence is needed, recent advances seem to have increased the reproductive outcomes in the poor prognosis patient. The key to success is individualization in all steps of ART treatment. Herein, we review the recent evidence for the management of POSEIDON groups 3 and 4.
Derechos:	Aquest document està subjecte a una llicència d'ús Creative Commons. Es permet la reproducció total o parcial, la distribució, la comunicació pública de l'obra i la creació d'obres derivades, fins i tot amb finalitats comercials, sempre i quan es reconegui l'autoria de l'obra original.
Lengua:	Anglès
Documento:	Article de revisió ; recerca ; Versió publicada
Materia:	Poor ovarian response ; Bologna criteria ; POSEIDON criteria ; Controlled ovarian stimulation ; Blastocyst ; Pregnancy ; ART calculator
Publicado en:	Frontiers in endocrinology, Vol. 10 (september 2019) , ISSN 1664-2392

DOI: 10.3389/fendo.2019.00614
PMID: 31572298

1.4 MB

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