Prevalence, clinical features and risk assessment of pre-diabetes in Spain : the prospective Mollerussa cohort study
Vilanova, María Belén (Consorci Sanitari de l'Anoia, Servei Català de la Salut)
Falguera, Mireia (Consorci Sanitari de l'Anoia, Servei Català de la Salut)
Marsal, Josep Ramon (Hospital Universitari Vall d'Hebron)
Rubinat, Esther (Universitat de Lleida)
Alcubierre, Nuria (Avantmèdic, & Centre Mèdic Pla d'Urgell, Mollerussa)
Catelblanco, Esmeralda (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol)
Granado-Casas, Minerva (Institut Universitari d'Investigació en Atenció Primària Jordi Gol)
Miró, Neus (Institut Català de la Salut)
Molló, Àngels (Institut Català de la Salut)
Mata-Cases, Manel (Institut Català de la Salut)
Franch-Nadal, Josep (Institut Català de la Salut)
Mauricio Puente, Dídac (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol)

Fecha:	2017
Resumen:	The Mollerussa prospective cohort was created to study pre-diabetes in a population-based sample from the primary care setting in the semirural area of Pla d'Urgell in Catalonia (Spain). The aims of the study were to assess the prevalence of pre-diabetes in our population, the likelihood to develop overt diabetes over time and to identify risk factors associated with the progression of the condition. The cohort includes 594 subjects randomly selected between March 2011 and July 2014 from our primary care population, who were older than 25 years, consented to participate and did not have a recorded diagnosis of diabetes. At baseline, we performed a clinical interview to collect demographic, clinical and lifestyle (including a nutritional survey) characteristics; carotid ultrasound imaging to assess subclinical cardiovascular disease was also performed, and a blood sample was collected, with an overall <5% rate of missing data. An additional blood draw was performed 12 months after initial recruitment to reassess laboratory results in patients initially identified as having pre-diabetes, with an 89. 6% retention rate. Several studies investigating various hypotheses are currently ongoing. All subjects recruited during the cohort creation will be followed long-term through annual extraction of data from health records stored in the electronic Clinical station in Primary Care database. The Mollerussa cohort will thus be a sound population-based sample for multiple future research projects to generate insights into the epidemiology and natural history of pre-diabetes in Spain.
Derechos:	Aquest document està subjecte a una llicència d'ús Creative Commons. Es permet la reproducció total o parcial, la distribució, la comunicació pública de l'obra i la creació d'obres derivades, sempre que no sigui amb finalitats comercials, i sempre que es reconegui l'autoria de l'obra original.
Lengua:	Anglès
Documento:	Article ; recerca ; Versió publicada
Publicado en:	BMJ open, Vol. 7 (june 2017) , ISSN 2044-6055

DOI: 10.1136/bmjopen-2016-015158
PMID: 28606902

8 p, 488.4 KB

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Documentos de investigación > Documentos de los grupos de investigación de la UAB > Centros y grupos de investigación (producción científica) > Ciencias de la salud y biociencias > Institut d'Investigació en Ciencies de la Salut Germans Trias i Pujol (IGTP)
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