Ischemic aetiology, self-reported frailty, and gender with respect to cognitive impairment in chronic heart failure patients
González Moneo, María Jesús (Institut Universitari d'Investigació en Atenció Primària Jordi Gol)
Sánchez-Benavides, Gonzalo (Institut Hospital del Mar d'Investigacions Mèdiques)
Verdu-Rotellar, José Maria (Universitat Autònoma de Barcelona. Departament de Medicina)
Cladellas Capdevila, Mercè (Institut Hospital del Mar d'Investigacions Mèdiques)
Bruguera Cortada, Jordi (Institut Hospital del Mar d'Investigacions Mèdiques)
Quiñones-Ubeda, Sonia (Institut Hospital del Mar d'Investigacions Mèdiques)
Enjuanes, Cristina (Institut Hospital del Mar d'Investigacions Mèdiques)
Peña-Casanova, J. (Jordi) (Institut Hospital del Mar d'Investigacions Mèdiques)
Comín-Colet, Josep (Institut Hospital del Mar d'Investigacions Mèdiques)

Data:	2016
Resum:	Decisive information on the parameters involved in cognitive impairment in patients with chronic heart failure is as yet lacking. Our aim was to determine the functional and psychosocial variables related with cognitive impairment using the mini-mental-state examination (MMSE) with age-and education-corrected scores. A cohort study of chronic heart failure patients included in an integrated multidisciplinary hospital/primary care program. The MMSE (corrected for age and education in the Spanish population) was administered at enrolment in the program. Analyses were performed in 525 patients. Demographic and clinical variables were collected. Comprehensive assessment included depression (Yesavage), family function (family APGAR), social network (Duke), dependence (Barthel Index), frailty (Barber), and comorbidities. Univariate and multivariate logistic regression were performed to determine the predictors of cognitive impairment. Cognitive impairment affected 145 patients (27. 6 %). Explanatory factors were gender (OR: 2. 77 (1. 75-4. 39) p < 0. 001), ischemic etiology (OR: 1. 99 (1. 25-3. 17) p = 0. 004), frailty (OR: 1. 58 (0. 99 to 2. 50, p = 0. 050), albumin > 3. 5 (OR: 0. 59 (0. 35-0. 99) p = 0. 048), and beta-blocker treatment (OR: 0. 36 (0. 17 to 0. 76, p = 0. 007)). No association was found between cognitive impairment and social support or family function. The observed prevalence of cognitive impairment using MMSE corrected scores was 27. 6 %. A global approach in the management of these patients is needed, especially focusing on women and patients with frailty, low albumin levels, and ischemic aetiology heart failure.
Drets:	Aquest document està subjecte a una llicència d'ús Creative Commons. Es permet la reproducció total o parcial, la distribució, la comunicació pública de l'obra i la creació d'obres derivades, fins i tot amb finalitats comercials, sempre i quan es reconegui l'autoria de l'obra original.
Llengua:	Anglès
Document:	Article ; recerca ; Versió publicada
Matèria:	Heart failure ; Cognitive symptoms ; Prevalence ; Comorbidity
Publicat a:	BMC Cardiovascular disorders, Vol. 16 (august 2016) , ISSN 1471-2261

DOI: 10.1186/s12872-016-0349-5
PMID: 27577747

10 p, 824.0 KB

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