On a Discrete SEIR Epidemic Model with Two-Doses Delayed Feedback Vaccination Control on the Susceptible
De la Sen, Manuel (Universidad del País Vasco)
Alonso-Quesada, Santiago (Universidad del País Vasco)
Ibeas, Asier (Universitat Autònoma de Barcelona. Departament de Telecomunicació i Enginyeria de Sistemes)
Nistal, Raul (Universidad del País Vasco)

Fecha:	2021
Resumen:	A new discrete susceptible-exposed-infectious-recovered (SEIR) epidemic model is presented subject to a feedback vaccination effort involving two doses. Both vaccination doses, which are subject to a non-necessarily identical effectiveness, are administrated by respecting a certain mutual delay interval, and their immunity effect is registered after a certain delay since the second dose. The delays and the efficacies of the doses are parameters, which can be fixed in the model for each concrete experimentation. The disease-free equilibrium point is characterized as well as its stability properties, while it is seen that no endemic equilibrium point exists. The exposed subpopulation is supposed to be infective eventually, under a distinct transmission rate of that of the infectious subpopulation. Some simulation examples are presented by using disease parameterizations of the COVID-19 pandemic under vaccination efforts requiring two doses.
Ayudas:	Agencia Estatal de Investigación RTI2018-094336-B-I00 Instituto de Salud Carlos III COV20/01213
Derechos:	Aquest document està subjecte a una llicència d'ús Creative Commons. Es permet la reproducció total o parcial, la distribució, la comunicació pública de l'obra i la creació d'obres derivades, fins i tot amb finalitats comercials, sempre i quan es reconegui l'autoria de l'obra original.
Lengua:	Anglès
Documento:	Article ; recerca ; Versió publicada
Materia:	Discrete epidemic model ; Delayed feedback vaccination control ; Vaccination doses ; COVID-19 pandemic
Publicado en:	Vaccines (Basel), Vol. 9, Num. 4 (April 2021) , art. 398, ISSN 2076-393X

DOI: 10.3390/vaccines9040398
PMID: 33919501

26 p, 3.6 MB

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