Google Scholar: citations
The Influence of Red Cabbage Extract Nanoencapsulated with Brassica Plasma Membrane Vesicles on the Gut Microbiome of Obese Volunteers
Garcia-Ibañez, Paula (Centro de Edafología y Biología Aplicada del Segura. Department of Food Science Technology)
Rosés, Carles (Universitat Autònoma de Barcelona. Servei de Genòmica)
Agudelo, Agatha (Universitat Politècnica de València. Departament de Biotecnologia)
Milagro, Fermin I. (Centro de Investigación Biomédica en Red de Fisiopatología de la Obesidad y Nutrición)
Barceló Vernet, Anna (Universitat Autònoma de Barcelona. Servei de Genòmica)
Viadel, Blanca (Technology Centre AINIA)
Nieto, Juan Antonio (Parque Tecnológico de Valencia)
Moreno, Diego A. (Centro de Edafología y Biología Aplicada del Segura)
Carvajal, Micaela (Centro de Edafología y Biología Aplicada del Segura)

Date: 2021
Abstract: The aim of the study was to evaluate the influence of the red cabbage extracts on the bioaccessibility of their isothiocyanates, and their effect on the intestinal microbiota using a dynamic model of human digestion treated with the gut microbiome of obese adults. The elicitation of red cabbage plants with methyl jasmonate (MeJA) duplicated the content of glucosinolates (GSLs) in the plant organs used for elaborating the encapsulated formula. The use of plasma membrane vesicles, according to a proper methodology and technology, showed a high retention of sulforaphane (SFN) and indol-3-carbinol (I3C) over the course of the 14-day digestion study. The microbiome was scarcely affected by the treatments in terms of microbiota composition or the Bacteroidetes/Firmicutes ratio, but a 3 to 4-fold increase was observed in the production of butyric acid with the encapsulated extract treatment. Based on our pilot red cabbage extract study, the consumption of this extract, mainly encapsulated, may play a potential role in the management of obesity in adults.
Grants: Agencia Estatal de Investigación AGL2016-80247-C2-1-R
Rights: Aquest document està subjecte a una llicència d'ús Creative Commons. Es permet la reproducció total o parcial, la distribució, la comunicació pública de l'obra i la creació d'obres derivades, fins i tot amb finalitats comercials, sempre i quan es reconegui l'autoria de l'obra original. Creative Commons
Language: Anglès
Document: Article ; recerca ; Versió publicada
Subject: Red cabbage ; Isothiocyanates ; Stability ; Encapsulation ; Gut microbiome ; Obesity
Published in: Foods, Vol. 10, Issue 5 (May 2021) , art. 1038, ISSN 2304-8158

DOI: 10.3390/foods10051038
PMID: 34068672


19 p, 1.9 MB

The record appears in these collections:
Articles > Research articles
Articles > Published articles

 Record created 2022-02-20, last modified 2025-12-23



   Favorit i Compartir