(De)Activation (Ir)Reversibly or Degradation : Dynamics of Post-Translational Protein Modifications in Plants
Muleya, Victor (Midlands State University. Department of Biochemistry)
Lois, L. Maria (Centre de Recerca en Agrigenòmica)
Chahtane, Hicham (Institut de Recherche Pierre Fabre)
Thomas, Ludivine
Chiapello, Marco (Institute for Sustainable Plant Protection)
Marondedze, Claudius (Midlands State University. Department of Biochemistry)

Date:	2022
Abstract:	The increasing dynamic functions of post-translational modifications (PTMs) within protein molecules present outstanding challenges for plant biology even at this present day. Protein PTMs are among the first and fastest plant responses to changes in the environment, indicating that the mechanisms and dynamics of PTMs are an essential area of plant biology. Besides being key players in signaling, PTMs play vital roles in gene expression, gene, and protein localization, protein stability and interactions, as well as enzyme kinetics. In this review, we take a broader but concise approach to capture the current state of events in the field of plant PTMs. We discuss protein modifications including citrullination, glycosylation, phosphorylation, oxidation and disulfide bridges, N-terminal, SUMOylation, and ubiquitination. Further, we outline the complexity of studying PTMs in relation to compartmentalization and function. We conclude by challenging the proteomics community to engage in holistic approaches towards identification and characterizing multiple PTMs on the same protein, their interaction, and mechanism of regulation to bring a deeper understanding of protein function and regulation in plants.
Grants:	Agencia Estatal de Investigación BIO2017-89874-R Ministerio de Economía y Competitividad SEV-2015-0533
Rights:	Aquest document està subjecte a una llicència d'ús Creative Commons. Es permet la reproducció total o parcial, la distribució, la comunicació pública de l'obra i la creació d'obres derivades, fins i tot amb finalitats comercials, sempre i quan es reconegui l'autoria de l'obra original.
Language:	Anglès
Document:	Article ; recerca ; Versió publicada
Subject:	Plant post-translational modifications ; Phosphorylation ; N -glycosylation ; Methionine oxidation ; N-terminal acetylation ; SUMOylation ; Ubiquitination
Published in:	Life, Vol. 12, Issue 2 (February 2022) , art. 324, ISSN 2075-1729

DOI: 10.3390/life12020324
PMID: 35207610

21 p, 885.8 KB

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Research literature > UAB research groups literature > Research Centres and Groups (research output) > Experimental sciences > CRAG (Centre for Research in Agricultural Genomics)
Articles > Research articles
Articles > Published articles