Incidence of myeloid neoplasms in Spain (2002-2013) : a population-based study of the Spanish network of cancer registries
Solans, Marta (Centro de Investigación Biomédica en Red de Epidemiología y Salud Pública)
Sanvisens, A. (Institut Germans Trias i Pujol. Institut de Recerca contra la Leucèmia Josep Carreras)
Ameijide, Alberto (Hospital Universitari Sant Joan de Reus (Tarragona))
Merino, S. (Asturias Cancer Registry)
Rojas, Dolores (Canary Islands Government)
Alemán, Araceli (Canary Islands Government)
Banqueri, E. (Castellón Cancer Registry)
Chico, Matilde (Ciudad Real Cancer Registry)
Marcos, A.I. (Cuenca Cancer Registry)
de Castro, Visitación (Basque Country Cancer Registry)
Gil, L. (Basque Country Cancer Registry)
López de Munain, Arantza (Basque Country Cancer Registry. Basque Government)
Puigdemont, Montse (Institut d'Investigació Biomèdica de Girona)
Sánchez, M.J. (University of Granada)
Perucha, J. (La Rioja Cancer Registry)
Ruiz-Armengol, P. (Mallorca Cancer Registry)
Chirlaque, María-Dolores (Murcia University)
Guevara, M. (Instituto de Investigación Sanitaria de Navarra)
Carulla, M. (Hospital Universitari Sant Joan de Reus (Tarragona))
Marcos-Gragera, Rafael (Institut Germans Trias i Pujol. Institut de Recerca contra la Leucèmia Josep Carreras)
Universitat Autònoma de Barcelona

Fecha:	2022
Resumen:	Comprehensive population-based data on myeloid neoplasms (MNs) are limited, mainly because some subtypes were not recognized as hematological cancers prior to the WHO publication in 2001, and others are too rare to allow robust estimates within regional studies. Herein, we provide incidence data of the whole spectrum of MNs in Spain during 2002-2013 using harmonized data from 13 population-based cancer registries. Cases (n = 17,522) were grouped following the HAEMACARE groupings and 2013-European standardized incidence rates (ASR), incidence trends, and estimates for 2021 were calculated. ASR per 100,000 inhabitants was 5. 14 (95% CI: 5. 00-5. 27) for myeloproliferative neoplasms (MPN), 4. 71 (95% CI: 4. 59-4. 84) for myelodysplastic syndromes (MDS), 3. 91 (95% CI: 3. 79-4. 02) for acute myeloid leukemia, 0. 83 (95% CI: 0. 78-0. 88) for MDS/MPN, 0. 35 (95% CI: 0. 32-0. 39) for acute leukemia of ambiguous lineage, and 0. 58 (95% CI: 0. 53-0. 62) for not-otherwise specified (NOS) cases. This study highlights some useful points for public health authorities, such as the remarkable variability in incidence rates among Spanish provinces, the increasing incidence of MPN, MDS, and MDS/MPN during the period of study, in contrast to a drop in NOS cases, and the number of cases expected in 2021 based on these data (8446 new MNs).
Ayudas:	Agència de Gestió d'Ajuts Universitaris i de Recerca 2017-SGR-00733 Ministerio de Economía y Competitividad PI15/00966
Nota:	This work was partially funded by the Josep Carreras Leukaemia Research Institute (Grant No.: FIJC1100); the Ministry of Science, Innovation and Universities, Carlos III Health Institute (ISCIII), Spain (Grant No.: PI15/00966); the Agency for Management of University and Research Grants, Government of Catalonia (Grant No.: 2017SGR00733); the CIBER of Epidemiology and Public Health (CIBERESP) ('Cohort-Real World Data' subprogram).
Derechos:	Tots els drets reservats.
Lengua:	Anglès
Documento:	Article ; recerca ; Versió publicada
Materia:	Adult ; Aged ; Aged, 80 and over ; Female ; Health Surveys ; Humans ; Incidence ; Leukemia, Myeloid, Acute ; Male ; Middle Aged ; Myelodysplastic Syndromes ; Myeloproliferative Disorders ; Registries ; Spain ; Time Factors
Publicado en:	Scientific reports, Vol. 12 Núm. 1 (december 2022) , p. 323, ISSN 2045-2322

DOI: 10.1038/s41598-021-03734-6
PMID: 35013373

11 p, 1.1 MB

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Documentos de investigación > Documentos de los grupos de investigación de la UAB > Centros y grupos de investigación (producción científica) > Ciencias de la salud y biociencias > Institut d'Investigació en Ciencies de la Salut Germans Trias i Pujol (IGTP) > Instituto de Investigación contra la Leucemia Josep Carreras
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