Risk Factors Involved in the High Incidence of Bladder Cancer in an Industrialized Area in North-Eastern Spain : A Case-Control Study
Caballero, José María ![Identificador ORCID](/img/uab/orcid.ico)
(Universitat Autònoma de Barcelona. Departament de Pediatria, Obstetrícia i Ginecologia i Medicina Preventiva i Salut Pública)
Gili, José M. (Hospital Universitari MútuaTerrassa (Terrassa, Catalunya))
Pereira, Juan C. (Hospital Universitari MútuaTerrassa (Terrassa, Catalunya))
Gomáriz, Alba (Hospital Universitari MútuaTerrassa (Terrassa, Catalunya))
Castillo, Carlos (Hospital Universitari MútuaTerrassa (Terrassa, Catalunya))
Martín-Baranera, Montserrat ![Identificador ORCID](/img/uab/orcid.ico)
(Consorci Sanitari Integral (Barcelona, Catalunya))
Fecha: |
2023 |
Resumen: |
Bladder cancer (BC) is the most common of the malignancies affecting the urinary tract. Smoking and exposure to occupational and environmental carcinogens are responsible for most cases. Vallès Occidental is a highly industrialized area in north-eastern Spain with one of the highest incidences of BC in men. We carried out a case-control study in order to identify the specific risk factors involved in this area. Three hundred and six participants were included (153 cases BC and 153 controls matched for age and sex): in each group, 89. 5% (n = 137) were male and the mean age was 71 years (range 30-91; SD = 10. 6). There were no differences between groups in family history, body mass index, or dietary habits. Independent risk factors for CV were smoking (OR 2. 08; 95% CI 1. 30-3. 32; p = 0. 002), the use of analgesics in nonsmokers (OR 10. 00; 95% CI 1. 28-78. 12; p = 0. 028), and profession (OR: 8. 63; 95% CI 1. 04-71. 94; p = 0. 046). The consumption of black and blond tobacco, the use of analgesics in nonsmokers, and occupational exposures are risk factors for the development of BC in this area, despite the reduction in smoking in the population and the extensive measures taken in the last few decades in major industries to prevent exposure to occupational carcinogens. |
Derechos: |
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Lengua: |
Anglès |
Documento: |
Article ; recerca ; Versió publicada |
Materia: |
Bladder cancer ;
Risk factors ;
Occupational exposure ;
Smoking ;
Analgesics |
Publicado en: |
Journal of clinical medicine, Vol. 12 (january 2023) , ISSN 2077-0383 |
DOI: 10.3390/jcm12020728
PMID: 36675657
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Registro creado el 2023-01-26, última modificación el 2023-10-10