Evolution of cortical geometry and its link to function, behaviour and ecology
Schwartz, Ernst (Medical University of Vienna. Department of Biomedical Imaging and Image-guided Therapy)
Nenning, Karl-Heinz (Medical University of Vienna. Department of Biomedical Imaging and Image-guided Therapy)
Heuer, Katja (Université Paris Cité. Institut Pasteur)
Jeffery, Nathan (University of Liverpool. Institute of Life Course & Medical Sciences)
Bertrand, Ornella C. (Institut Català de Paleontologia Miquel Crusafont)
Toro, Roberto (Université Paris Cité. Institut Pasteur)
Kasprian, Gregor (Medical University of Vienna. Department of Biomedical Imaging and Image-guided Therapy)
Prayer, Daniela (Medical University of Vienna. Department of Biomedical Imaging and Image-guided Therapy)
Langs, Georg (Medical University of Vienna. Department of Biomedical Imaging and Image-guided Therapy)

Fecha:	2023
Resumen:	Studies in comparative neuroanatomy and of the fossil record demonstrate the influence of socio-ecological niches on the morphology of the cerebral cortex, but have led to oftentimes conflicting theories about its evolution. Here, we study the relationship between the shape of the cerebral cortex and the topography of its function. We establish a joint geometric representation of the cerebral cortices of ninety species of extant Euarchontoglires, including commonly used experimental model organisms. We show that variability in surface geometry relates to species' ecology and behaviour, independent of overall brain size. Notably, ancestral shape reconstruction of the cortical surface and its change during evolution enables us to trace the evolutionary history of localised cortical expansions, modal segregation of brain function, and their association to behaviour and cognition. We find that individual cortical regions follow different sequences of area increase during evolutionary adaptations to dynamic socio-ecological niches. Anatomical correlates of this sequence of events are still observable in extant species, and relate to their current behaviour and ecology. We decompose the deep evolutionary history of the shape of the human cortical surface into spatially and temporally conscribed components with highly interpretable functional associations, highlighting the importance of considering the evolutionary history of cortical regions when studying their anatomy and function.
Ayudas:	European Commission 101033485 European Commission 765148 European Commission 792611
Derechos:	Aquest document està subjecte a una llicència d'ús Creative Commons. Es permet la reproducció total o parcial, la distribució, la comunicació pública de l'obra i la creació d'obres derivades, fins i tot amb finalitats comercials, sempre i quan es reconegui l'autoria de l'obra original.
Lengua:	Anglès
Documento:	Article ; recerca ; Versió publicada
Materia:	Evolution ; Neuroscience
Publicado en:	Nature communications, Vol. 14 (April 2023) , art. 2252, ISSN 2041-1723

DOI: 10.1038/s41467-023-37574-x
PMID: 37080952

19 p, 4.8 MB

El registro aparece en las colecciones:
Documentos de investigación > Documentos de los grupos de investigación de la UAB > Centros y grupos de investigación (producción científica) > Ciencias > Institut Català de Paleontologia Miquel Crusafont (ICP)
Artículos > Artículos de investigación
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