Atherosclerosis, Cardiovascular Disease, and COVID-19 : A Narrative Review
Vilaplana-Carnerero, Carles (Institut Universitari d'Investigació en Atenció Primària Jordi Gol)
Giner-Soriano, Maria (Institut Universitari d'Investigació en Atenció Primària Jordi Gol)
Domínguez, Ángela (Universitat de Barcelona)
Morros, Rosa (Institut Universitari d'Investigació en Atenció Primària Jordi Gol)
Pericas, Carles (Universitat de Barcelona)
Álamo-Junquera, Dolores (Hospital Universitari Vall d'Hebron)
Toledo, Diana (Universitat de Barcelona)
Gallego, Carmen (Universitat de Barcelona)
Redondo, Ana (Hospital Universitari de Bellvitge)
Grau, Maria (Institut d'Investigacions Biomèdiques August Pi i Sunyer)
Universitat Autònoma de Barcelona

Date:	2023
Abstract:	Atherosclerosis is a chronic inflammatory and degenerative process that mainly occurs in large- and medium-sized arteries and is morphologically characterized by asymmetric focal thickenings of the innermost layer of the artery, the intima. This process is the basis of cardiovascular diseases (CVDs), the most common cause of death worldwide. Some studies suggest a bidirectional link between atherosclerosis and the consequent CVD with COVID-19. The aims of this narrative review are (1) to provide an overview of the most recent studies that point out a bidirectional relation between COVID-19 and atherosclerosis and (2) to summarize the impact of cardiovascular drugs on COVID-19 outcomes. A growing body of evidence shows that COVID-19 prognosis in individuals with CVD is worse compared with those without. Moreover, various studies have reported the emergence of newly diagnosed patients with CVD after COVID-19. The most common treatments for CVD may influence COVID-19 outcomes. Thus, their implication in the infection process is briefly discussed in this review. A better understanding of the link among atherosclerosis, CVD, and COVID-19 could proactively identify risk factors and, as a result, develop strategies to improve the prognosis for these patients.
Rights:	Aquest document està subjecte a una llicència d'ús Creative Commons. Es permet la reproducció total o parcial, la distribució, la comunicació pública de l'obra i la creació d'obres derivades, fins i tot amb finalitats comercials, sempre i quan es reconegui l'autoria de l'obra original.
Language:	Anglès
Document:	Article ; recerca ; Versió publicada
Subject:	Atherosclerosis ; Bidirectional link ; Cardiovascular disease ; Cardiovascular disease treatments ; COVID-19 ; Long COVID
Published in:	Biomedicines, Vol. 11 (april 2023) , ISSN 2227-9059

DOI: 10.3390/biomedicines11041206
PMID: 37189823

14 p, 533.6 KB

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