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| Home > Articles > Published articles > Ghost admixture in eastern gorillas |
(Institute of Evolutionary Biology) (University of Vienna. Department of Evolutionary Anthropology) (University of Vienna. Department of Evolutionary Anthropology) (Institute of Evolutionary Biology) (Swedish Museum of Natural History) (Institute of Evolutionary Biology) (Institute of Evolutionary Biology) (Institute of Evolutionary Biology) (Institute of Evolutionary Biology) (Institute of Evolutionary Biology) (Monash University Malaysia) (Wellcome Trust Sanger Institute (Regne Unit)) (University of California. Department of Ecology and Evolutionary Biology) (University of California. Department of Ecology and Evolutionary Biology) (University of Edinburgh) (Institute of Evolutionary Biology) (Institut Català de Paleontologia Miquel Crusafont) (Institute of Evolutionary Biology)
| Date: | 2023 |
| Abstract: | Archaic admixture has had a substantial impact on human evolution with multiple events across different clades, including from extinct hominins such as Neanderthals and Denisovans into modern humans. In great apes, archaic admixture has been identified in chimpanzees and bonobos but the possibility of such events has not been explored in other species. Here, we address this question using high-coverage whole-genome sequences from all four extant gorilla subspecies, including six newly sequenced eastern gorillas from previously unsampled geographic regions. Using approximate Bayesian computation with neural networks to model the demographic history of gorillas, we find a signature of admixture from an archaic 'ghost' lineage into the common ancestor of eastern gorillas but not western gorillas. We infer that up to 3% of the genome of these individuals is introgressed from an archaic lineage that diverged more than 3 million years ago from the common ancestor of all extant gorillas. This introgression event took place before the split of mountain and eastern lowland gorillas, probably more than 40 thousand years ago and may have influenced perception of bitter taste in eastern gorillas. When comparing the introgression landscapes of gorillas, humans and bonobos, we find a consistent depletion of introgressed fragments on the X chromosome across these species. However, depletion in protein-coding content is not detectable in eastern gorillas, possibly as a consequence of stronger genetic drift in this species. |
| Grants: | European Commission 864203 Ministerio de Economía y Competitividad PID2021-126004NB-100 Agència de Gestió d'Ajuts Universitaris i de Recerca FI_B100131 Agència de Gestió d'Ajuts Universitaris i de Recerca 2021/SGR-00177 Ministerio de Ciencia e Innovación PRE2018-083966 |
| Rights: | Aquest document està subjecte a una llicència d'ús Creative Commons. Es permet la reproducció total o parcial, la distribució, la comunicació pública de l'obra i la creació d'obres derivades, fins i tot amb finalitats comercials, sempre i quan es reconegui l'autoria de l'obra original.  |
| Language: | Anglès |
| Document: | Article ; recerca ; Versió publicada |
| Published in: | Nature ecology & evolution, Vol. 7 (July 2023) , p. 1503-1514, ISSN 2397-334X |
