Oxytocin measurements in saliva : an analytical perspective
López-Arjona, Marina (Universitat Autònoma de Barcelona. Departament de Ciència Animal i dels Aliments)
Botía, María (Universidad de Murcia. Laboratorio Interdisciplinario de Análisis Clínicos Interlab)
Martínez-Subiela, Silvia (Universidad de Murcia. Laboratorio Interdisciplinario de Análisis Clínicos Interlab)
Cerón, José Joaquín (Universidad de Murcia. Laboratorio Interdisciplinario de Análisis Clínicos Interlab)

Date:	2023
Abstract:	Oxytocin has traditionally been known for its physiological effects on muscle contraction associated with birth and lactation, but in the last years is widely used as a biomarker of "positive experiences" in psychology and behavior. Different types of samples have been used for oxytocin measurements with saliva samples having the particular advantage of an easy and non-stressful collection. However, the low concentration of oxytocin in saliva can represent a limitation for its use. For this reason, sensitive assays and even a previous sample treatment in some cases are required for saliva oxytocin quantification. In addition, the lack of standardized and generally agreed-upon approach to peripheral oxytocin measurement leads to large discrepancies between different laboratories, that use different sample treatment protocols and different assays. The main objectives of this review are to describe the current status of the use of saliva for oxytocin measurement, provide details of the different sample processing techniques that can be applied and inform about the analytical techniques and assays available in different animal species, and also in humans for comparative purposes. It is expected that this information can contribute to an increase in the knowledge about the measurements of oxytocin in saliva and to its wider use in the future.
Grants:	Ministerio de Ciencia e Innovación FJC2021-047105-I Agencia Estatal de Investigación PDC2021-121291-I00
Rights:	Aquest document està subjecte a una llicència d'ús Creative Commons. Es permet la reproducció total o parcial, la distribució, la comunicació pública de l'obra i la creació d'obres derivades, fins i tot amb finalitats comercials, sempre i quan es reconegui l'autoria de l'obra original.
Language:	Anglès
Document:	Article ; recerca ; Versió publicada
Subject:	Enzyme immunoassay ; Extraction ; Oxytocin ; Saliva ; Welfare
Published in:	BMC veterinary research, Vol. 19 (july 2023) , ISSN 1746-6148

DOI: 10.1186/s12917-023-03661-w
PMID: 37507690

11 p, 1.1 MB

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