Serological survey of Leishmania infantum in apparently healthy dogs in different areas of Spain
Baxarias, Marta (Universitat Autònoma de Barcelona. Departament de Medicina i Cirurgia Animals)
Mateu, Cristina (Ecuphar Veterinaria SLU)
Miró, Guadalupe (Universidad Complutense de Madrid)
Solano Gallego, Laia (Universitat Autònoma de Barcelona. Departament de Medicina i Cirurgia Animals)

Date:	2023
Abstract:	Canine leishmaniosis caused by Leishmania infantum is an endemic disease in Spain. The dog is considered the main reservoir, and the detection of specific serum antibodies against L. infantum antigen is the most used technique for diagnosing this infection. The LEISCAN LEISHMANIA ELISA test is a commercialized enzyme-linked immunosorbent assay for the detection and measurement of canine anti- Leishmania serum antibodies. The aim of this study was to assess seroprevalence results of apparently healthy dogs in different areas of Spain using LEISCAN. Collection of sera from 5451 apparently healthy dogs was performed between 2020 and 2021 in different areas of Spain. Dogs were of adult age (≥12 months), were not previously diagnosed with clinical leishmaniosis or vaccinated against Leishmania and did not present clinical signs compatible with L. infantum infection. LEISCAN was performed following the manufacturer's protocol. The overall seroprevalence was 5. 5%. The highest seroprevalences were found in the Southeast of Spain: Comunidad Valenciana (14%) and Región de Murcia (14%), whereas the lowest seroprevalences were found in Northern Spain: Galicia (1%), Navarra (2%) and Castilla y León (2%) (p -value <0. 001). In conclusion, the seroprevalence for L. infantum in apparently healthy dogs in Spain varied from almost no infection to being over 10%. Graphical Abstract:.
Note:	Altres ajuts: acords transformatius de la UAB
Rights:	Aquest document està subjecte a una llicència d'ús Creative Commons. Es permet la reproducció total o parcial, la distribució, i la comunicació pública de l'obra, sempre que no sigui amb finalitats comercials, i sempre que es reconegui l'autoria de l'obra original. No es permet la creació d'obres derivades.
Language:	Anglès
Document:	Article ; recerca ; Versió publicada
Subject:	Canine ; Diagnosis ; ELISA ; Leishmaniosis ; Seroprevalence
Published in:	Veterinary Medicine and Science, Vol. 9 (july 2023) , p. 1980-1988, ISSN 2053-1095

DOI: 10.1002/vms3.1172
PMID: 37438910

9 p, 336.7 KB

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