Complex Evolutionary History With Extensive Ancestral Gene Flow in an African Primate Radiation
Jensen, Axel (Uppsala University. Department of Ecology and Genetics, Animal Ecology)
Swift, Frances (University of Edinburgh. School of Biological Sciences)
de Vries, Dorien (University of Salford. School of Science, Engineering and Environment)
Beck, Robin (University of Salford. School of Science, Engineering & Environment)
Kuderna, Lukas (Illumina Inc)
Knauf, Sascha (Federal Research Institute for Animal Health)
Chuma, Idrissa S. (Tanzania National Parks)
Keyyu, Julius (Tanzania Wildlife Research Institute)
Kitchener, Andrew (University of Edinburgh. University of Edinburgh)
Farh, Kai How (Illumina Inc)
Rogers, Jeffrey (Baylor College of Medicine. Human Genome Sequencing Center)
Marques-Bonet, Tomas, 1975- (Institut Català de Paleontologia Miquel Crusafont)
Detwiler, Kate (Florida Atlantic University. Department of Biological Sciences)
Roos, Christian (Leibniz Institute for Primate Research. German Primate Center)
Guschanski, Katerina (Uppsala University. Department of Ecology and Genetics)

Data:	2023
Resum:	Understanding the drivers of speciation is fundamental in evolutionary biology, and recent studies highlight hybridization as an important evolutionary force. Using whole-genome sequencing data from 22 species of guenons (tribe Cercopithecini), one of the world's largest primate radiations, we show that rampant gene flow characterizes their evolutionary history and identify ancient hybridization across deeply divergent lineages that differ in ecology, morphology, and karyotypes. Some hybridization events resulted in mitochondrial introgression between distant lineages, likely facilitated by cointrogression of coadapted nuclear variants. Although the genomic landscapes of introgression were largely lineage specific, we found that genes with immune functions were overrepresented in introgressing regions, in line with adaptive introgression, whereas genes involved in pigmentation and morphology may contribute to reproductive isolation. In line with reports from other systems that hybridization might facilitate diversification, we find that some of the most species-rich guenon clades are of admixed origin. This study provides important insights into the prevalence, role, and outcomes of ancestral hybridization in a large mammalian radiation.
Drets:	Aquest document està subjecte a una llicència d'ús Creative Commons. Es permet la reproducció total o parcial, la distribució, la comunicació pública de l'obra i la creació d'obres derivades, sempre que no sigui amb finalitats comercials, i sempre que es reconegui l'autoria de l'obra original.
Llengua:	Anglès
Document:	Article ; recerca ; Versió publicada
Matèria:	Phylogenomics ; Speciation ; Ancient hybridization ; Evolutionary genomics ; Mammalian radiation ; Guenon
Publicat a:	Molecular Biology and Evolution, Vol. 40, Issue 12 (December 2023) , art. msad247

DOI: 10.1093/molbev/msad247
PMID: 37987553

19 p, 8.7 MB

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