Integrated optical devices for lab-on-a-chip biosensing applications
Estévez, M. Carmen (Institut Català de Nanociència i Nanotecnologia)
Alvarez, Mar (Institut Català de Nanociència i Nanotecnologia)
Lechuga, Laura M. (Institut Català de Nanociència i Nanotecnologia)

Date:	2012
Abstract:	The application of portable, easy-to-use and highly sensitive lab-on-a-chip biosensing devices for real-time diagnosis could offer significant advantages over current analytical methods. Integrated optics-based biosensors have become the most suitable technology for lab-on-chip integration due to their ability for miniaturization, their extreme sensitivity, robustness, reliability, and their potential for multiplexing and mass production at low cost. This review provides an extended overview of the state-of-the-art in integrated photonic biosensors technology including interferometers, grating couplers, microring resonators, photonic crystals and other novel nanophotonic transducers. Particular emphasis has been placed on describing their real biosensing applications and wherever possible a comparison of the sensing performances between each type of device is included. The way towards achieving operative lab-on-a-chip platform incorporating the photonic biosensors is also reviewed. Concluding remarks regarding the future prospects and potential impact of this technology are also provided.
Grants:	Ministerio de Industria, Turismo y Comercio TSI-020301-2008-11
Note:	Altres ajuts: Fundación M. Botín ; Juan de la Cierva Program
Rights:	Tots els drets reservats.
Language:	Anglès
Document:	Article de revisió ; recerca ; Versió acceptada per publicar
Subject:	Biofunctionalization ; Evanescent wave detection ; Lab-on-a-chip ; Photonic biosensors ; Silicon photonics
Published in:	Laser & photonics reviews, Vol. 6, Issue 4 (July 2012) , p. 463-487, ISSN 1863-8899

DOI: 10.1002/lpor.201100025

Postprint 46 p, 703.3 KB

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Research literature > UAB research groups literature > Research Centres and Groups (research output) > Experimental sciences > Catalan Institute of Nanoscience and Nanotechnology (ICN2)
Articles > Research articles
Articles > Published articles