Quality of Life in Older Patients after a Heart Failure Hospitalization : Results from the SENECOR Study
Luiso, Daniele (Institut Hospital del Mar d'Investigacions Mèdiques)
Herrero-Torrus, Marta (Institut Hospital del Mar d'Investigacions Mèdiques)
Badosa, Neus (Institut Hospital del Mar d'Investigacions Mèdiques)
Roqueta, Cristina (Institut Hospital del Mar d'Investigacions Mèdiques)
Ruiz Bustillo, Sonia (Universitat Pompeu Fabra. Departament de Medicina i Ciències de la Vida)
Belarte Tornero, Laia Carla (Institut Hospital del Mar d'Investigacions Mèdiques)
Valdivielso Moré, Sandra (Institut Hospital del Mar d'Investigacions Mèdiques)
Morales, Ronald O. (Institut Hospital del Mar d'Investigacions Mèdiques)
Vázquez Ibar, Olga (Institut Hospital del Mar d'Investigacions Mèdiques)
Farré, Núria (Institut Hospital del Mar d'Investigacions Mèdiques)
Universitat Autònoma de Barcelona

Fecha:	2022
Resumen:	Information about health-related quality of life (HRQoL) in heart failure (HF) in older adults is scarce. We aimed to describe the HRQoL of the SENECOR study cohort, a single-center, randomized trial comparing the effects of multidisciplinary intervention by a geriatrician and a cardiologist (intervention group) to that of a cardiologist alone (control group) in older patients with a recent HF hospitalization. HRQoL was assessed by the short version of the disease-specific Kansas Cardiomyopathy Questionnaire (KCCQ-12) in 141 patients at baseline and was impaired (KCCQ-12 < 75) in almost half of the cohort. Women comprised 50% of the population, the mean age was 82. 2 years, and two-thirds of patients had preserved ejection fraction. Comorbidities were highly prevalent. Patients with impaired HRQoL had a worse NYHA functional class, a lower NT-proBNP, a lower Barthel index, and a higher Clinical Frailty Scale. One-year all-cause mortality was 22. 7%, significantly lower in the group with good-to-excellent HRQoL (14. 5% vs. 30. 6%; hazard ratio 0. 28; 95% confidence interval 0. 10-0. 78; p = 0. 014). In the group with better HRQoL, all-cause hospitalization was lower, and there was a trend towards lower HF hospitalization. The KCCQ-12 questionnaire can provide inexpensive prognostic information even in older patients with HF. (Funded by grant Primitivo de la Vega, Fundación MAPFRE. ClinicalTrials number, NCT03555318).
Derechos:	Aquest document està subjecte a una llicència d'ús Creative Commons. Es permet la reproducció total o parcial, la distribució, la comunicació pública de l'obra i la creació d'obres derivades, fins i tot amb finalitats comercials, sempre i quan es reconegui l'autoria de l'obra original.
Lengua:	Anglès
Documento:	Article ; recerca ; Versió publicada
Materia:	Heart failure ; Older patients ; Prognosis ; Quality of life
Publicado en:	Journal of clinical medicine, Vol. 11 (may 2022) , ISSN 2077-0383

DOI: 10.3390/jcm11113035
PMID: 35683423

12 p, 889.7 KB

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