cmv1 -Mediated Resistance to CMV in Melon Can Be Overcome by Mixed Infections with Potyviruses
Giordano, Andrea Mariana (Centre de Recerca en Agrigenòmica)
Ferriol, Inmaculada (Centre de Recerca en Agrigenòmica)
Lopez-Moya, Juan Jose (Centre de Recerca en Agrigenòmica)
Martín-Hernández, Ana Montserrat (Centre de Recerca en Agrigenòmica)

Date:	2023
Abstract:	Resistance to cucumber mosaic virus (CMV) strain LS in melon is controlled by the gene cmv1, which restricts phloem entry. In nature, CMV is commonly found in mixed infections, particularly with potyviruses, where a synergistic effect is frequently produced. We have explored the possibility that this synergism could help CMV-LS to overcome cmv1 -mediated resistance. We demonstrate that during mixed infection with a potyvirus, CMV-LS is able to overcome cmv1 -controlled resistance and develop a systemic infection and that this ability does not depend on an increased accumulation of CMV-LS in mechanically inoculated cotyledons. Likewise, during a mixed infection initiated by aphids, the natural vector of both cucumoviruses and potyviruses that can very efficiently inoculate plants with a low number of virions, CMV-LS also overcomes cmv1 -controlled resistance. This indicates that in the presence of a potyvirus, even a very low amount of inoculum, can be sufficient to surpass the resistance and initiate the infection. These results indicate that there is an important risk for this resistance to be broken in nature as a consequence of mixed infections, and therefore, its deployment in elite cultivars would not be enough to ensure a long-lasting resistance.
Grants:	European Commission 793090 Agencia Estatal de Investigación RTI2018-097665-B-C21 Agencia Estatal de Investigación PID2019-105692RB-I00 Ministerio de Economía y Competitividad SEV-2015-0533 Ministerio de Ciencia e Innovación CEX2019-000902-S
Rights:	Aquest document està subjecte a una llicència d'ús Creative Commons. Es permet la reproducció total o parcial, la distribució, la comunicació pública de l'obra i la creació d'obres derivades, fins i tot amb finalitats comercials, sempre i quan es reconegui l'autoria de l'obra original.
Language:	Anglès
Document:	Article ; recerca ; Versió publicada
Subject:	Cucumovirus ; Potyvirus ; Genetic resistance ; Mixed infections ; Melon
Published in:	Viruses, Vol. 15, Issue 9 (August 2023) , art. 1792, ISSN 1999-4915

DOI: 10.3390/v15091792
PMID: 37766198

10 p, 1.1 MB

The record appears in these collections:
Research literature > UAB research groups literature > Research Centres and Groups (research output) > Experimental sciences > CRAG (Centre for Research in Agricultural Genomics)
Articles > Research articles
Articles > Published articles