Kidney stones in renal transplant recipients : A systematic review Litiasis en receptores de trasplante renal: revisión sistemática
Piana, Alberto (Università di Torino)
Basile, Giuseppe (Universitat Autònoma de Barcelona)
Masih, Sonia (Centro Médico de la Universidad de Toledo)
Bignante, Gabriele (Università di Torino)
Uleri, Alessandro (Universitat Autònoma de Barcelona)
Gallioli, Andrea (Institut de Recerca Sant Pau)
Prudhomme, Thomas (Hospital Universitario de Rangueil)
Boissier, Romain (Hospital Universitario La Concepción)
Pecoraro, Alessio (Università degli Studi di Firenze)
Campi, Riccardo (Università degli Studi di Firenze)
Di Dio, Michele (Hospital Annunziata)
Alba, Stefano (Hospital Annunziata)
Breda, Alberto (Institut de Recerca Sant Pau)
Territo, Angelo (Universitat Autònoma de Barcelona)

Fecha:	2024
Resumen:	Introduction: Lithiasis in renal graft recipients might be a dangerous condition with a potential risk of organ function impairment. Evidence acquisition: A systematic literature search was conducted through February 2023. The primary objective was to assess the incidence of lithiasis in kidney transplant (KT) recipients. The secondary objective was to assess the timing of stone formation, localization and composition of stones, possible treatment options, and the incidence of graft loss. Evidence synthesis: A total of 41 non-randomized studies comprising 699 patients met our inclusion criteria. The age at lithiasis diagnosis ranged between 29-53 years. Incidence of urolithiasis ranged from 0. 1 to 6. 3%, usually diagnosed after 12 months from KT. Most of the stones were diagnosed in the calyces or in the pelvis. Calcium oxalate composition was the most frequent. Different treatment strategies were considered, namely active surveillance, ureteroscopy, percutaneous/combined approach, or open surgery. 15. 73% of patients were submitted to extracorporeal shock wave lithotripsy (ESWL), while 26. 75% underwent endoscopic lithotripsy or stone extraction. 18. 03% of patients underwent percutaneous nephrolithotomy whilst 3. 14% to a combined approach. Surgical lithotomy was performed in 5. 01% of the cases. Global stone-free rate was around 80%. Conclusions: Lithiasis in kidney transplant is a rare condition usually diagnosed after one year after surgery and mostly located in the calyces and renal pelvis, more frequently of calcium oxalate composition. Each of the active treatments is associated with good results in terms of stone-free rate, thus the surgical technique should be chosen according to the patient's characteristics and surgeon preferences.
Derechos:	Aquest document està subjecte a una llicència d'ús Creative Commons. Es permet la reproducció total o parcial, la distribució, i la comunicació pública de l'obra, sempre que no sigui amb finalitats comercials, i sempre que es reconegui l'autoria de l'obra original. No es permet la creació d'obres derivades.
Lengua:	Castellà
Documento:	Article de revisió ; recerca ; Versió publicada
Materia:	Trasplante renal ; Tratamiento ; Urolitiasis
Publicado en:	Actas Urologicas Espanolas, Vol. 48 Núm. 1 (enero 2024) , p. 79-104, ISSN 0210-4806

DOI: 10.1016/j.acuro.2023.07.003

26 p, 1.3 MB

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