Role of routine uterine artery Doppler at 18-22 and 24-28 weeks' gestation following routine first-trimester screening for pre-eclampsia
Bonacina, Erika (Hospital Universitari Vall d'Hebron)
del Barco, Ester (Hospital Universitari Vall d'Hebron)
Farràs Llobet, Alba (Hospital Universitari Vall d'Hebron)
Cullell-Dalmau, Marta (Hospital Universitari Vall d'Hebron)
Garcia Cancela, Esperanza (Consorci Sanitari de Terrassa)
Gleeson-Vallbona, L. (Hospital Universitari de Girona Doctor Josep Trueta)
Serrano, Berta (Hospital Universitari Vall d'Hebron)
Armengol-Alsina, Mireia (Hospital Universitari Vall d'Hebron)
Catalán, Sara (Hospital Universitari Vall d'Hebron)
Hernádez, A. (Hospital Universitari Vall d'Hebron)
San José Moya, Marta (Hospital Universitari Vall d'Hebron)
Miserachs, M. (Hospital Universitari Vall d'Hebron)
Millan, Pilar (Consorci Sanitari de Terrassa)
García Manau, Pablo (Hospital Universitari Vall d'Hebron)
Carreras Moratonas, Elena (Hospital Universitari Vall d'Hebron)
Mendoza, Manel (Universitat Autònoma de Barcelona. Departament de Pediatria, Obstetrícia i Ginecologia i de Medicina Preventiva i Salut Pública)

Data:	2024
Resum:	To assess the performance of mean uterine artery pulsatility index (UtA-PI) at 18-22 and 24-28 weeks of gestation in the prediction of pre-eclampsia (PE) and small-for-gestational age (SGA), and its role in reassessing the risk of PE and SGA in pregnancies screened for PE in the first trimester. This was a retrospective observational cohort study of 4464 women with singleton pregnancy screened routinely for PE in the first trimester, using the Gaussian algorithm, from March 2019 to May 2021, and who underwent UtA-PI assessment at 18-22 gestational weeks. Women were categorized as low risk or high risk based on the risk index obtained after first-trimester screening for PE. In high-risk patients, UtA-PI was also assessed at 24-28 weeks of gestation. Sensitivity, specificity, positive predictive value, negative predictive value (NPV), positive likelihood ratio, negative likelihood ratio and area under the receiver-operating-characteristics curve were calculated to assess the performance of UtA-PI at 18-22 and 24-28 weeks in predicting PE and SGA in the high-risk group. In all participants, different UtA-PI percentiles at 18-22 or 24-28 weeks, or their combination, were analyzed to explore their role in reassessing the risk of PE and SGA following first-trimester PE screening. The performance of UtA-PI at 18-22 and 24-28 weeks in the high-risk group was good for predicting preterm PE and preterm SGA, and excellent for predicting early-onset PE and early-onset SGA, with an NPV of.
Drets:	Aquest document està subjecte a una llicència d'ús Creative Commons. Es permet la reproducció total o parcial, la distribució, i la comunicació pública de l'obra, sempre que no sigui amb finalitats comercials, i sempre que es reconegui l'autoria de l'obra original. No es permet la creació d'obres derivades.
Llengua:	Anglès
Document:	Article ; recerca ; Versió publicada
Matèria:	First trimester ; Pre-eclampsia ; Screening ; Uterine artery Doppler
Publicat a:	Ultrasound in obstetrics & gynecology, Vol. 65 (december 2024) , p. 63-70, ISSN 1469-0705

DOI: 10.1002/uog.29145
PMID: 39639487

8 p, 499.7 KB

El registre apareix a les col·leccions:
Articles > Articles de recerca
Articles > Articles publicats