Spatial scale influences the distribution of viral diversity in the eukaryotic virome of the mosquito Culex pipiens
Gil, Patricia (Université de Montpellier)
Exbrayat, Antoni (Université de Montpellier)
Loire, Etienne (Université de Montpellier)
Rakotoarivony, Ignace (Université de Montpellier)
Charriat, Florian (Université de Montpellier)
Morel, Côme (Université de Montpellier)
Baldet, Thierry (Université de Montpellier)
Boisseau, Michel (Université de Montpellier)
Marie, Albane (EID Mediterranée)
Frances, Benoît (EID Mediterranée)
L'Ambert, Gregory (EID Mediterranée)
Bessat, Mohamed (Alexandria University)
Otify, Yehia (Alexandria University)
Goffredo, Maria (Istituto Zooprofilattico Sperimentale dell'Abruzzo e del Molise 'G. Caporale')
Mancini, Giuseppe (Istituto Zooprofilattico Sperimentale dell'Abruzzo e del Molise 'G. Caporale')
Busquets, Núria (Unitat mixta d'investigació IRTA-UAB en Sanitat Animal. Centre de Recerca en Sanitat Animal)
Birnberg, Lotty (Unitat mixta d'investigació IRTA-UAB en Sanitat Animal. Centre de Recerca en Sanitat Animal)
Talavera Forcades, Sandra (Unitat mixta d'investigació IRTA-UAB en Sanitat Animal. Centre de Recerca en Sanitat Animal)
Aranda Pallero, Carles (Servei de Control de Mosquits del Consell Comarcal del Baix Llobregat)
Ayari, Emna (Université Tunis El Manar)
Mejri, Selma (Université Tunis El Manar)
Sghaier, Soufien (Université Tunis El Manar)
Bennouna, Amal (Hassan II Agronomy & Veterinary Institute)
El Rhaffouli, Hicham (FAR Military Health Service)
Balenghien, Thomas (Hassan II Agronomy & Veterinary Institute)
Chlyeh, Ghita (Institute of Agronomy and Veterinary Medicine Hassan II)
Fassi Fihri, Ouafaa (Hassan II Agronomy & Veterinary Institute)
Reveillaud, Julie (Université de Montpellier)
Simonin, Yannick (Université de Montpellier)
Eloit, Marc (Université Paris Cité. Institut Pasteur)
Gutierrez, Serafin (Université de Montpellier)

Data:	2023
Resum:	Our knowledge of the diversity of eukaryotic viruses has recently undergone a massive expansion. This diversity could influence host physiology through yet unknown phenomena of potential interest to the fields of health and food production. However, the assembly processes of this diversity remain elusive in the eukaryotic viromes of terrestrial animals. This situation hinders hypothesis-driven tests of virome influence on host physiology. Here, we compare taxonomic diversity between different spatial scales in the eukaryotic virome of the mosquito Culex pipiens. This mosquito is a vector of human pathogens worldwide. The experimental design involved sampling in five countries in Africa and Europe around the Mediterranean Sea and large mosquito numbers to ensure a thorough exploration of virus diversity. A group of viruses was found in all countries. This core group represented a relatively large and diverse fraction of the virome. However, certain core viruses were not shared by all host individuals in a given country, and their infection rates fluctuated between countries and years. Moreover, the distribution of coinfections in individual mosquitoes suggested random co-occurrence of those core viruses. Our results also suggested differences in viromes depending on geography, with viromes tending to cluster depending on the continent. Thus, our results unveil that the overlap in taxonomic diversity can decrease with spatial scale in the eukaryotic virome of C. pipiens. Furthermore, our results show that integrating contrasted spatial scales allows us to identify assembly patterns in the mosquito virome. Such patterns can guide future studies of virome influence on mosquito physiology.
Ajuts:	European Commission FP7-613996 Vmerge
Drets:	Aquest document està subjecte a una llicència d'ús Creative Commons. Es permet la reproducció total o parcial, la distribució, la comunicació pública de l'obra i la creació d'obres derivades, sempre que no sigui amb finalitats comercials, i sempre que es reconegui l'autoria de l'obra original.
Llengua:	Anglès
Document:	Article ; recerca ; Versió publicada
Matèria:	Virome ; Mosquito ; Culex pipiens ; Metagenomics
Publicat a:	Virus Evolution, Vol. 9 (august 2023) , ISSN 2057-1577

DOI: 10.1093/ve/vead054
PMID: 37719779

14 p, 5.3 MB

El registre apareix a les col·leccions:
Documents de recerca > Documents dels grups de recerca de la UAB > Centres i grups de recerca (producció científica) > Ciències de la salut i biociències > Centre de Recerca en Sanitat Animal (CReSA-IRTA)
Articles > Articles de recerca
Articles > Articles publicats