A 1024-Channel 10-Bit 36-μW/ch CMOS ROIC for Multiplexed GFET-Only Sensor Arrays in Brain Mapping
Cisneros-Fernández, Jose (Institut de Microelectrònica de Barcelona)
Garcia Cortadella, Ramon (Institut Català de Nanociència i Nanotecnologia)
Illa, Xavi (Institut de Microelectrònica de Barcelona)
Martinez-Aguilar, Javier (Institut de Microelectrònica de Barcelona)
Paetzold, Jens (Multi Channel Systems GmbH)
Mohrlok, Rainer (Multi Channel Systems GmbH)
Kurnoth, Marius (Multi Channel Systems GmbH)
Jeschke, Christoph (Multi Channel Systems GmbH)
Terés Terés, Lluís (Universitat Autònoma de Barcelona. Departament de Microelectrònica i Sistemes Electrònics)
Garrido, Jose (Institut Català de Nanociència i Nanotecnologia)
Guimerà Brunet, Anton (Centro de Investigación Biomédica en Red de Bioingeniería, Biomateriales y Nanomedicina)
Serra Graells, Francesc (Institut de Microelectrònica de Barcelona)

Date:	2021
Abstract:	This paper presents a 1024-channel neural read-out integrated circuit (ROIC) for solution-gated GFET sensing probes in massive muECoG brain mapping. The proposed time-domain multiplexing of GFET-only arrays enables low-cost and scalable hybrid headstages. Low-power CMOS circuits are presented for the GFET analog frontend, including a CDS mechanism to improve preamplifier noise figures and 10-bit 10-kS/s A/D conversion. The 1024-channel ROIC has been fabricated in a standard 1. 8-V 0. 18-mum CMOS technology with 0. 012 mm 2 and 36 mu W per channel. An automated methodology for the in-situ calibration of each GFET sensor is also proposed. Experimental ROIC tests are reported using a custom FPGA-based muECoG headstage with 16times 32 and 32times 32 GFET probes in saline solution and agar substrate. Compared to state-of-art neural ROICs, this work achieves the largest scalability in hybrid platforms and it allows the recording of infra-slow neural signals.
Grants:	European Commission 732032
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Language:	Anglès
Document:	Article ; recerca ; Versió acceptada per publicar
Subject:	Integrated circuits ; ROIC ; Neural recording ; µECoG ; GFET ; CMOS ; TDM ; CDS ; ADC ; Headstage
Published in:	IEEE Transactions on Biomedical Circuits and Systems, Vol. 15, Issue 5 (October 2021) , p. 860-876, ISSN 1940-9990

DOI: 10.1109/TBCAS.2021.3113556

Postprint 17 p, 5.3 MB

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Research literature > UAB research groups literature > Research Centres and Groups (research output) > Experimental sciences > Catalan Institute of Nanoscience and Nanotechnology (ICN2)
Articles > Research articles
Articles > Published articles