Enhancing the First-Pass Effect in Acute Stroke : The Impact of Stent Retriever Characteristics
Murias, Eduardo (Universidad de Oviedo)
Puig, Josep (Hospital Clínic i Provincial de Barcelona)
Serna-Candel, Carmen (Hospital General Universitario de Alicante (Alacant, País Valencià))
Gonzalez, Eva Maria (Hospital Universitario de Cruces (Barakaldo, País Basc))
Moreu, Manuel (Hospital Clínico San Carlos (Madrid))
Jiménez-Gómez, Elvira (Hospital Universitario Reina Sofía (Còrdova, Espanya))
San Román, Luis (Hospital Clínic i Provincial de Barcelona)
Aparici Robles, Fernando (Hospital Universitari i Politècnic La Fe (València))
Terceño, Mikel (Hospital Universitari de Girona Doctor Josep Trueta)
Mosqueira, Antonio (Complejo Hospitalario Universitario de Santiago de Compostela)
Aixut Lorenzo, Sonia (Hospital Clínic i Provincial de Barcelona)
Romero-Saucedo, Veredas (Hospital Universitario Reina Sofía (Còrdova, Espanya))
Mendez, Jose Carlos (Hospital Universitario Ramón y Cajal (Madrid))
Sagredo-Barra, Antonio (Hospital General Universitario de Alicante (Alacant, País Valencià))
Aguilar Tejedor, Yeray (Complejo Hospitalario Universitario Insular Materno Infantil (Las Palmas de Gran Canaria))
Espinosa de Rueda, Mariano (Hospital Universitario Virgen de la Arrixaca (Múrcia))
Castaño Blázquez, Miguel Angel (Hospital Universitario de Salamanca)
Bashir, Saima (Hospital Universitari de Girona Doctor Josep Trueta)
Rodríguez Castro, José (Hospital Universitario Central de Asturias)
Lopez-Frías, A. (Hospital Clínico San Carlos (Madrid))
Jiménez, Jose María (Hospital Universitario Central de Asturias)
Chaviano, Juan (Hospital Universitario Central de Asturias)
Maestro, Víctor (Hospital Universitario Central de Asturias)
Manso, Javier (Hospital Universitario de Cruces (Barakaldo, País Basc))
Lopez-Rueda, Antonio (Hospital Universitari de Bellvitge)
Remollo Friedemann, Sebastián (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol)
Morales-Caba, Lluis (Hospital Universitari i Politècnic La Fe (València))
Comas-Cufí, Marc (Universitat de Girona)
Vega, Pedro (Hospital Universitario Central de Asturias)

Fecha:	2024
Resumen:	Introduction: Although stentrievers (SRs) have been a mainstay of mechanical thrombectomy (MT), and current guidelines recommend the use of SRs in the treatment of large vessel occlusion stroke (LVO), there is a paucity of studies in the literature comparing SRs directly against each other in terms of mechanical and functional properties. Timely access to endovascular therapy and the ability to restore intracranial flow in a safe, efficient, and efficacious manner have been critical to the success of MT. This study aimed to investigate the impact of contemporary SR characteristics, including model, brand, size, and length, on the first-pass effect (FPE) in patients with acute ischemic stroke. Methods: Consecutive patients with M1 occlusion treated with a single SR+BGC were recruited from the ROSSETTI registry. The primary outcome was the FPE that was defined as modified (mFPE) or true (tFPE) for the achievement of modified thrombolysis in cerebral infarction (mTICI) grades 2b-3 or 3 after a single device pass, respectively. We compared patients who achieved mFPE with those who achieved tFPE according to SR characteristics. Results: We included 610 patients (52. 3% female and 47. 7% male, mean age 75. 1 ± 13. 62 years). mFPE was achieved in 357 patients (58. 5%), whereas tFPE was achieved in 264 (43. 3%). There was no significant association between SR characteristics and mFPE or tFPE. Specifically, the SR size did not show a statistically significant relationship with improvement in FPE. Similarly, the length of the SR did not yield significant differences in the mFPE and tFPE, even when the data were grouped. Conclusions: Our data indicate that contemporary SR-mediated thrombectomy characteristics, including model, brand, size, and length, do not significantly affect the FPE.
Derechos:	Aquest document està subjecte a una llicència d'ús Creative Commons. Es permet la reproducció total o parcial, la distribució, la comunicació pública de l'obra i la creació d'obres derivades, fins i tot amb finalitats comercials, sempre i quan es reconegui l'autoria de l'obra original.
Lengua:	Anglès
Documento:	Article ; recerca ; Versió publicada
Materia:	Thrombectomy ; Stroke ; Endovascular ; Stentriever
Publicado en:	Journal of clinical medicine, Vol. 13 Núm. 11 (May 2024) , p. 3123, ISSN 2077-0383

DOI: 10.3390/jcm13113123
PMID: 38892834

10 p, 243.8 KB

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Documentos de investigación > Documentos de los grupos de investigación de la UAB > Centros y grupos de investigación (producción científica) > Ciencias de la salud y biociencias > Institut d'Investigació en Ciencies de la Salut Germans Trias i Pujol (IGTP)
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