Eliminating antibiotics by white-rot-fungi Trametes versicolor from manure solids and synthetic wastewater
Tan, Zewen (Universitat Autònoma de Barcelona. Departament d'Enginyeria Química, Biològica i Ambiental)
Beltrán-Flores, Eduardo (Universitat Autònoma de Barcelona. Departament d'Enginyeria Química, Biològica i Ambiental)
Ramos-Meza, Gisselle D. (Universitat Autònoma de Barcelona. Departament d'Enginyeria Química, Biològica i Ambiental)
Alonso, Lucas L. (Institut Català de Recerca de l'Aigua)
Sarrà i Adroguer, Montserrat (Universitat Autònoma de Barcelona. Departament d'Enginyeria Química, Biològica i Ambiental)

Date:	2025
Abstract:	Antibiotics have been abused in livestock as veterinary drug and feed additive. Their incomplete metabolization by animals resulted in heavy accumulation in livestock manure, and therefore they can pose a threat to the environment. In this study, the mechanism of three antibiotics (oxytetracycline (OTC), sulfadiazine (SDZ), enrofloxacin (ENR)) removal/biodegradation by Trametes versicolor pellets in air-pulse fluidized-bed reactor was explored, and the effects of wood immobilized T. versicolor on four antibiotics (OTC, SDZ, ENR and chloramphenicol (CAP)) removal in solid cow manures were evaluated. T. versicolor could remove OTC, SDZ, ENR through adsorption and biodegradation, with the removal efficiency at 92 % and 98 % in 21 h and 98 % after 68 h, respectively. The removal kinetics of those three antibiotics fitted well with the first-order kinetic model, with the removal constant k at -0. 238 h, -0. 102 h and -0. 023 h, respectively. T. versicolor could biodegrade those three antibiotics using laccase and cytochrome P450 system with the order SDZ ≈ OTC > ENR. Furthermore, wood immobilized T. versicolor promoted SDZ, OTC, ENR and chloramphenicol (CAP) antibiotic biodegradation in cow manure, especially in high inoculation ratio (wood immobilized T. versicolor: solid cow manures = 1:2). This study revealed the mechanism of simultaneous SDZ, OTC, ENR and CAP antibiotic removal/biodegradation by white-rot fungi T. versicolor even by wood immobilized T. versicolor in solid cow manures, which provide a theoretical basis for future application of biological removal of antibiotics present in wastewater and solid manures.
Grants:	Agencia Estatal de Investigación PID2022-138929OB-I00 Agencia Estatal de Investigación TED2021-130639B-I00 Agencia Estatal de Investigación PID2020-115456RB-I00 Agència de Gestió d'Ajuts Universitaris i de Recerca 2021/SGR-01282 Agència de Gestió d'Ajuts Universitaris i de Recerca 2021/SGR-01283
Note:	Altres ajuts: acords transformatius de la UAB
Rights:	Aquest document està subjecte a una llicència d'ús Creative Commons. Es permet la reproducció total o parcial, la distribució, la comunicació pública de l'obra i la creació d'obres derivades, sempre que no sigui amb finalitats comercials, i sempre que es reconegui l'autoria de l'obra original.
Language:	Anglès
Document:	Article ; recerca ; Versió publicada
Subject:	Antibiotics biodegradation ; Biodegradation products ; Fluidized-bed reactor ; Wood immobilized fungi ; Solid cow manure
Published in:	Environmental pollution, Vol. 378 (August 2025) , art. 126504, ISSN 1873-6424

DOI: 10.1016/j.envpol.2025.126504

10 p, 1.4 MB

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