Recommendations for the measurement of sexual steroids in clinical practice. A position statement of SEQC ML /SEEN/SEEP
Casals, Gregori (Hospital Clínic i Provincial de Barcelona)
Ferrer Costa, Roser (Hospital Universitari Vall d'Hebron)
Urgell, Eulàlia (Hospital de la Santa Creu i Sant Pau (Barcelona, Catalunya))
Escobar-Morreale, Héctor F. (Hospital de la Santa Creu i Sant Pau (Barcelona, Catalunya))
Argente, Jesús (Hospital Universitari Vall d'Hebron)
Sesmilo, Gemma (Hospital Universitario Ramón y Cajal (Madrid))
Biagetti, Betina (Hospital Infantil Universitario Niño Jesús (Madrid))
Universitat Autònoma de Barcelona

Date:	2023
Abstract:	The proper clinical approach to a wide range of disorders relies on the availability of accurate, reproducible laboratory results for sexual steroids measured using methods with a high specificity and sensitivity. The chemiluminescent immunoassays currently available have analytical limitations with significant clinical implications. This position statement reviews the current limitations of laboratory techniques for the measurement of estradiol and testosterone and their impact on diverse clinical scenarios. A set of recommendations are provided to incorporate steroid hormone analysis by mass spectrometry in national health systems. International societies have recommended this methodology for a decade.
Rights:	Aquest document està subjecte a una llicència d'ús Creative Commons. Es permet la reproducció total o parcial, la distribució, la comunicació pública de l'obra i la creació d'obres derivades, fins i tot amb finalitats comercials, sempre i quan es reconegui l'autoria de l'obra original.
Language:	Anglès
Document:	Article ; recerca ; Versió publicada
Subject:	Estradiol ; Immunoassay ; Mass spectrometry ; Sexual steroids ; Testosterone
Published in:	Advances in Laboratory Medicine, Vol. 4 (march 2023) , p. 52-60, ISSN 2628-491X

DOI: 10.1515/almed-2023-0020
PMID: 37359897

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