Reciprocal effects of stable and temporary components of neuroticism and affective disorders : results of a longitudinal cohort study
Spinhoven, Philip (Leiden University)
Penelo Werner, Eva (Universitat Autònoma de Barcelona. Departament de Psicobiologia i de Metodologia de les Ciències de la Salut)
Rooij, Mark de (Leiden University)
Penninx, Brenda W. (Leiden University Medical Center. Department of Psychiatry)
Ormel, Johan (University Medical Center Groningen. Department of Psychiatry)

Títol variant:	Reciprocal effects of neuroticism and affective disorders
Data:	2014
Descripció:	32 pàg.
Resum:	Background. Mostly cross-sectional studies show that neuroticism is strongly associated with affective disorders. We investigated whether neuroticism and affective disorders are mutually reinforcing each other over time, setting off a potential downward spiral. Method. A total of 2981 adults aged 18-65, consisting of healthy controls, persons with a prior history of affective disorders, and persons with a current affective disorder were assessed at T1 and 2 years (T2) and 4-years (T3) later. At each wave affective disorders according to DSM-IV criteria were assessed with the CIDI and neuroticism with the NEO-FFI. Results. Using structural equation models the association of distress disorders (i. e. , dysthymia, depressive disorder, generalized anxiety disorder) and fear disorders (i. e. , social anxiety disorder, panic disorder, agoraphobia without panic) with neuroticism could be attributed to three components: (a) a strong correlation of the stable components of distress and fear disorders with the stable trait component of neuroticism; (b) a modest contemporaneous association of change in distress and fear disorders with change in neuroticism; (c) a small to modest delayed effect of change in distress and fear disorders on change in neuroticism. Moreover, neuroticism scores in participants newly affected at T2 but remitted at T3 did not differ from their premorbid scores at T1. Conclusions. Our results do not support a positive feedback cycle of changes in psychopathology and changes in neuroticism. In the context of a, strongly correlated relative stability of neuroticism and affective disorders, only modest contemporaneous and small to modest delayed effects of psychopathology on neuroticism were observed.
Nota:	Altres ajuts: The infrastructure for the NESDA study (www.nesda.nl) is funded through the Geestkracht program of the Netherlands Organisation for Health Research and Development (Zon-Mw, grant number 10-000-1002) and is supported by participating universities and mental health care organizations (VU University Medical Center, GGZ inGeest, Arkin, Leiden University Medical Center, GGZ Rivierduinen, University Medical Center Groningen, Lentis, GGZ Friesland, GGZ Drenthe, Scientific Institute for Quality of Healthcare (IQ healthcare), Netherlands Institute for Health Services Research (NIVEL) and Netherlands Institute of Mental Health and Addiction (Trimbos).
Drets:	Aquest document està subjecte a una llicència d'ús Creative Commons. Es permet la reproducció total o parcial, la distribució, i la comunicació pública de l'obra, sempre que no sigui amb finalitats comercials, i sempre que es reconegui l'autoria de l'obra original. No es permet la creació d'obres derivades.
Llengua:	Anglès
Document:	Article ; recerca ; Versió acceptada per publicar
Matèria:	Anxiety ; Depression ; Neuroticism ; Scar effect ; State effect
Publicat a:	Psychological Medicine, Vol. 44 (2014) , p. 337-348, ISSN 1469-8978

DOI: 10.1017/S0033291713000822

Postprint 32 p, 888.8 KB

El registre apareix a les col·leccions:
Articles > Articles de recerca
Articles > Articles publicats