Impact of Serum Progesterone Levels on Pregnancy Outcomes in Patients Undergoing Artificial Endometrial Preparation for Embryo Transfer
Tarasconi, Diego (Fundación Fertty Assisted Reproduction Clinic)
Checa, Miguel Angel (Institut Hospital del Mar d'Investigacions Mèdiques)
Julià, Mireia (Institut Hospital del Mar d'Investigacions Mèdiques)
Espinós, Juan José (Universitat Autònoma de Barcelona. Departament de Pediatria, Obstetrícia i Ginecologia i de Medicina Preventiva i Salut Pública)

Date:	2022
Abstract:	In this retrospective cohort study, we examined the impact of measuring serum progesterone (P) levels on pregnancy outcomes in patients undergoing artificial endometrial preparation and embryo transfer (ET). We analyzed 342 ET cycles at the blastocyst stage, either from autologous or donated oocytes, in a private fertility care center. ET cycles were performed after an artificial endometrial preparation with a sequential administration of estradiol valerate followed by vaginal micronized progesterone. In the study population, when serum P levels were lower than 10. 0 ng/ml the day prior to ET, a subcutaneous preparation of P was added, attempting to bring its levels to the luteal phase support. Interestingly, in the case of autologous ET, the rates of early pregnancy loss were reduced by measuring and eventually supplementing serum P levels.
Rights:	Aquest document està subjecte a una llicència d'ús Creative Commons. Es permet la reproducció total o parcial, la distribució, la comunicació pública de l'obra i la creació d'obres derivades, fins i tot amb finalitats comercials, sempre i quan es reconegui l'autoria de l'obra original.
Language:	Anglès
Document:	Article ; recerca ; Versió publicada
Subject:	Serum progesterone ; Blastocyst transfer ; Early pregnancy loss ; Frozen embryo transfer ; Endometrial preparation
Published in:	Journal of Endocrinology and Thyroid Research, 2022 , ISSN 2573-2188

DOI: 10.19080/JETR.2022.06.5556947

5 p, 422.2 KB

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