Second-generation preimplantation genetic testing for aneuploidy in assisted reproduction: a SWOT analysis
Bellver José (Universitat de València)
Bosch, Ernesto (Universitat de València)
Espinós, Juan José (Hospital de la Santa Creu i Sant Pau (Barcelona, Catalunya))
Fabregues, Francisco (Hospital Clínic i Provincial de Barcelona)
Fontes, Juan (Hospital Universitario Virgen de las Nieves (Granada))
García-Velasco, Juan A. (IVI RMA Madrid)
Llácer, Joaquin (Instituto Bernabeu Alicante)
Requena, Antonio (IVI RMA Madrid)
Checa, Miguel Angel (Parc de Salut MAR de Barcelona)
Universitat Autònoma de Barcelona. Departament de Pediatria, Obstetrícia i Ginecologia i de Medicina Preventiva i Salut Pública

Date:	2019
Abstract:	cond-generation preimplantation genetic testing for aneuploidy (PGT-A 2. 0) in patients with an unfavourable reproductive and IVF prognosis is becoming common practice, with the aim of improving reproductive outcomes. However, there is still no clear evidence on the possible advantages and drawbacks with regard to this procedure. In this discussion paper, based on a SWOT (strengths, weaknesses, opportunities, threats) analysis, the different aspects of this strategy are evaluated. Current evidence suggests that PGT-A 2. 0 should not at present have an indiscriminate application, but it might be indicated in cases in which the risk of aneuploidy is increased.
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Language:	Anglès
Document:	Article ; recerca ; Versió acceptada per publicar
Subject:	Preimplantation genetic testing ; Assisted reproduction ; Infertility ; Implantation ; Live birth ; Blastocyst biopsy
Published in:	Reproductive biomedicine online, 2019 , ISSN 1472-6491

DOI: 10.1016/j.rbmo.2019.07.037

Postprint 43 p, 1.1 MB

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