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Long-lasting symptoms in borderline personality disorder : Defining an emergent population with differential clinical and therapeutic features
Casellas-Pujol, Elisabet (Universitat Autònoma de Barcelona)
Soler, Joaquim (Institut de Recerca Sant Pau)
Schmidt, Carlos (Hospital de la Santa Creu i Sant Pau (Barcelona, Catalunya))
Soriano Pacheco, José (Universitat Autònoma de Barcelona. Departament de Psiquiatria i de Medicina Legal)
Pascual, Juan Carlos (Universitat Autònoma de Barcelona. Departament de Psiquiatria i de Medicina Legal)

Fecha: 2024
Resumen: Although the clinical symptoms of borderline personality disorder (BPD) tend to remit over time, a substantial proportion continues to present "long-lasting symptoms" (LLS). This term refers to individuals who present some degree of clinical improvement, but low mood, feelings of emptiness, and poor psychosocial adjustment typically persist. The aim of this study was to compare the sociodemographic, clinical, and therapeutic variables in individuals with BPD with and without LLS. A total of 620 participants with BPD were included and subdivided into two groups: non-LLS group (n = 549, mean age = 28. 02 [6. 1] and range, 18-40 years) and LLS group (n = 71, mean age = 44. 69 [3. 6] and range, 41-56 years). The groups were compared in sociodemographic, clinical, and drug treatment characteristics. We also evaluated the impact of dialectical behavioral therapy-skills training (DBT-ST) on polypharmacy. The prevalence of individuals with long-lasting BPD symptoms increased significantly over a 20-year period (from <1% to 16%). The LLS group was characterized by less clinical severity, higher comorbidity with affective disorders but lower comorbidity with eating disorders, more disability, and more medication taking. Patients with LLS who received DBT-ST experienced a significant decrease in the use of benzodiazepines and the number of medications prescribed compared with those who did not receive DBT-ST. Clinicians should be aware of the specific features of older patients with BPD in order to better identify and address their specific therapeutic needs.
Ayudas: Instituto de Salud Carlos III PI19/00087
Instituto de Salud Carlos III PI21/00505
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Lengua: Anglès
Documento: Article ; recerca ; Versió acceptada per publicar
Materia: Borderline Personality Disorder ; Long-lasting symptoms ; Recovery ; Polypharmacy ; Skills training
Publicado en: Personality and Mental Health, Vol. 18 Núm. 3 (August 2024) , p. 248-258, ISSN 1932-863X

DOI: 10.1002/pmh.1614


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Documentos de investigación > Documentos de los grupos de investigación de la UAB > Centros y grupos de investigación (producción científica) > Ciencias de la salud y biociencias > Institut de Recerca Sant Pau
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 Registro creado el 2025-10-06, última modificación el 2025-10-21



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