Successful Volume Control of Invasive Pituitary Adenoma Tumor With Pasireotide : A New Horizon for a Challenging Disease
Elhadd, Tarik (Hamad General Hospital (Doha, Catar))
Ibrahim, Shahd I. (Hamad General Hospital (Doha, Catar))
Abdelmahmuod, Elabbass (Universitat Autònoma de Barcelona. Departament de Medicina)
Webb, S. M. 1952- (Universitat Autònoma de Barcelona. Departament de Medicina)

Date:	2025
Abstract:	A 62-year-old Sudanese female was diagnosed with a nonfunctioning pituitary adenoma in 2006. Despite undergoing 3 transsphenoidal surgeries and radiotherapy, her tumor persisted, causing debilitating symptoms, including headaches and visual defects. As a last resort, she was treated with pasireotide, a second-generation somatostatin analog with a broader receptor affinity than first-generation drugs. Over 6 months, the tumor mass was stabilized, and her symptoms, including headaches, disappeared. This case demonstrates a potential new therapeutic possibility for treating resistant pituitary adenoma with pasireotide, offering hope for patients when traditional treatments fail.
Rights:	Aquest document està subjecte a una llicència d'ús Creative Commons. Es permet la reproducció total o parcial, la distribució, la comunicació pública de l'obra i la creació d'obres derivades, fins i tot amb finalitats comercials, sempre i quan es reconegui l'autoria de l'obra original.
Language:	Anglès
Document:	Article ; recerca ; Versió publicada
Subject:	Pituitary tumor ; Nonfunctioning pituitary tumor ; Resistant invasive pituitary adenoma ; Pasireotide
Published in:	JCEM Case Reports, Vol. 3 (april 2025) , ISSN 2755-1520

DOI: 10.1210/jcemcr/luaf075
PMID: 40255441

5 p, 472.9 KB

The record appears in these collections:
Articles > Research articles
Articles > Published articles