Inter-organ communication : pathways and targets to cardioprotection and neuro-protection. A report from the 12th Hatter Cardiovascular Institute workshop
Pearce, L. (University College London)
Galán-Arriola, C. (Centro Nacional de Investigaciones Cardiovasculares Carlos III (CNIC))
Bell, R.M. (University College London)
Carr, R.D. (Ulster University)
Cunningham, J. (University College London)
Davidson, Sean M. (University College London)
Ghosh, A.K. (University College London)
Giesz, S. (University College London)
Golforoush, P. (University College London)
Gourine, A.V. (University College London)
Hermann, D.M. (University of Duisburg-Essen)
Heusch, Gerd (University of Duisburg-Essen)
Kalkhoran, S.B. (The Hatter Cardiovascular Institute. University College London)
Lecour, Sandrine (University of Cape Town)
Lukhna, K. (University of Cape Town)
Ntsekhe, M. (University of Cape Town)
Sack, M.N. (National Institutes of Health (Bethesda, Estats Units d'Amèrica))
Unwin, R.J. (University College London)
Vilahur, Gemma (Institut de Recerca Sant Pau)
Walker, J.M. (University College London)
Yellon, D.M. (University of Cape Town)
Universitat Autònoma de Barcelona. Departament de Medicina

Fecha:	2025
Resumen:	A long-standing aim in the setting of various pathologies including acute myocardial infarction, chronic kidney disease (CKD), and ischaemic stroke, has been to identify successful approaches to augment cellular and organ protection. Although the continual evolution and refinement of ideas over the past few decades has allowed the field to progress, we are yet to realise successful clinical translation of this concept. The 12th Hatter Cardiovascular Workshop identified a number of important points and key questions for future research relating to cardio- and neuro-protection and interorgan communication. Specific topics that were discussed include the 'cardio-metabolic-renal' axis of organ protection, the parasympathetic signalling hypothesis, the role of the coronary microvasculature in myocardial infarction, the RISK pathway of cardioprotection, extracellular vesicles and the way forward, the future for clinical studies of remote ischaemic conditioning, and new experimental models for cardio-oncology investigations.
Derechos:	Aquest document està subjecte a una llicència d'ús Creative Commons. Es permet la reproducció total o parcial, la distribució, la comunicació pública de l'obra i la creació d'obres derivades, fins i tot amb finalitats comercials, sempre i quan es reconegui l'autoria de l'obra original.
Lengua:	Anglès
Colección:	Ibanez, B.
Documento:	Article ; recerca ; Versió publicada
Materia:	Brain ; Cardio-oncology ; Cytoprotection ; Heart ; Ischaemia ; Kidney ; Reperfusion ; Signalling
Publicado en:	Basic Research in Cardiology, Vol. 120 Núm. 2 (april 2025) , p. 287-299, ISSN 1435-1803

DOI: 10.1007/s00395-024-01094-6
PMID: 39681732

13 p, 3.0 MB

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Documentos de investigación > Documentos de los grupos de investigación de la UAB > Centros y grupos de investigación (producción científica) > Ciencias de la salud y biociencias > Institut de Recerca Sant Pau
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