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| Página principal > Artículos > Artículos publicados > Impact of the new EASO obesity definition on the detection of atheromatosis in subjects with low-to-moderate cardiovascular risk |
| Fecha: | 2025 |
| Resumen: | Traditional body mass index (BMI) does not adequately reflect adipose tissue distribution and associated cardiovascular (CV) risk. To improve risk stratification, the European Association for the Study of Obesity (EASO) proposes to extend the diagnosis of obesity to include individuals with a BMI of 25-30 kg/m², a waist-to-height ratio (WtHR) ≥0. 5, and any obesity-related complication. To examine whether this new definition of obesity can better identify the presence of subclinical atheromatosis disease (SAD) in terms of arterial plaque burden compared to the classical BMI-based definition. A cross-sectional including 8,330 participants from the ILERVAS project (ClinicalTrials. gov Identifier: ), aged 45-70 years with low-to-moderate CV risk and no previous CV disease, was included. Obesity was classified using traditional (BMI ≥ 30 kg/m²) and new definitions. Atherosclerosis was assessed through Doppler ultrasound of carotid and femoral arteries. Logistic regression models adjusted for cardiovascular risk factors were used to evaluate associations between obesity definitions and SAD. The new definition increased obesity prevalence from 37. 2% to 71. 7%. It also revealed higher detection of atheromatous plaques (72. 9% vs. 68. 6%, p. |
| Ayudas: | Instituto de Salud Carlos III PI21/00462 Instituto de Salud Carlos III PI21/01099 Instituto de Salud Carlos III PMP21/00109 Instituto de Salud Carlos III PMP22/00073 Instituto de Salud Carlos III PI23/00237 Agencia Estatal de Investigación PID2022-141964OB-I00 Generalitat de Catalunya 2021SGR00990 |
| Derechos: | Aquest document està subjecte a una llicència d'ús Creative Commons. Es permet la reproducció total o parcial, la distribució, la comunicació pública de l'obra i la creació d'obres derivades, fins i tot amb finalitats comercials, sempre i quan es reconegui l'autoria de l'obra original. |
| Lengua: | Anglès |
| Documento: | Article ; recerca ; Versió publicada |
| Materia: | Obesity ; Central adiposity ; Subclinical atheromatous disease ; Cardiovascular risk factors ; Waist-to-height ratio |
| Publicado en: | Frontiers in endocrinology, Vol. 16 (October 2025) , art. 1689960, ISSN 1664-2392 |
11 p, 592.1 KB |