Development and validation of predictive model for identification of MLH1 and MSH2 mutation carriers in Lynch syndrome
Balmaña Gelpí, Judith
Brunet, Joan, dir.
Baselga Torres, Josep, 1959-2021, dir. (Hospital Universitari Vall d'Hebron)
Universitat Autònoma de Barcelona. Departament de Medicina

Imprint:	Bellaterra : Universitat Autònoma de Barcelona, 2010
Abstract:	Lynch syndrome is the most frequent hereditary colorectal cancer syndrome. It is estimated to account for 1-3% of all colorectal cancer patients and endometrial cancer patients14. Many studies have been published to attempt to address the prevalence of this syndrome and the heterogeneity is huge, mostly because population-based studies are few, geographical distribution of carriers may differ due to founder mutations, or studies may include testing of different type of mismatch repair (MMR) genes15-28. Nevertheless, it is important to highlight that definition of the syndrome has not always been homogeneous and it has hampered its recognition and diagnosis.
Note:	Descripció del recurs: 19 gener 2011
Note:	Tesi doctoral - Universitat Autònoma de Barcelona. Facultat de Medicina, Departament de Medicina, 2009
Note:	Bibliografia
Rights:	Aquest material està protegit per drets d'autor i/o drets afins. Podeu utilitzar aquest material en funció del que permet la legislació de drets d'autor i drets afins d'aplicació al vostre cas. Per a d'altres usos heu d'obtenir permís del(s) titular(s) de drets.
Language:	Anglès
Document:	Tesi doctoral
Subject:	Lynch, Síndrome de
ISBN:	9788469373286

Adreça alternativa:: https://hdl.handle.net/10803/4562

132 p, 3.3 MB

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Research literature > Doctoral theses