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22 p, 3.1 MB Three different signal amplification strategies for the impedimetric sandwich detection of thrombin / Ocaña Tejada, Cristina (Universitat Autònoma de Barcelona. Grup Sensors i Biosensors) ; Valle Zafra, Manuel del (Universitat Autònoma de Barcelona. Departament de Química)
In this work, we report a comparative study on three highly specific amplification strategies for the ultrasensitive detection of thrombin with the use of aptamer sandwich protocol. The protocol consisted on the use of a first thrombin aptamer immobilized on the electrode surface, the recognition of thrombin protein, and the reaction with a second biotinylated thrombin aptamer forming the sandwich. [...]
2016 - 10.1016/j.aca.2016.01.027
Analytica chimica acta, Vol. 912 (March 2016) , p. 117-124  

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