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7 p, 969.7 KB Gabapentin and Pregabalin and Risk of Atrial Fibrillation in the Elderly : A Population-Based Cohort Study in an Electronic Prescription Database / Ortiz de Landaluce, Leticia (Servei Català de la Salut. Gerència de Prestacions Farmacèutiques i Accés al Medicament) ; Carbonell, Pere (Servei Català de la Salut. Gerència de Prestacions Farmacèutiques i Accés al Medicament) ; Asensio Ostos, Carmen (Fundació Institut Català de Farmacologia) ; Escoda, Núria (Servei Català de la Salut. Gerència de Prestacions Farmacèutiques i Accés al Medicament) ; López, Pilar (Servei Català de la Salut. Gerència de Prestacions Farmacèutiques i Accés al Medicament) ; Laporte Rosselló, Joan-Ramón (Fundació Institut Català de Farmacologia) ; Universitat Autònoma de Barcelona
Gabapentin and pregabalin are widely prescribed to elderly people, but data on their pharmacokinetics, safety, and efficacy in this population are scarce. Neurological adverse effects are common. Atrial fibrillation (AF) associated with their use has been described in several case reports and case series, but the incidence is unknown. [...]
2018 - 10.1007/s40264-018-0695-6
Drug Safety, Vol. 41 (june 2018) , p. 1325-1331  
Detailed record - Creative Commons

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