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5 p, 359.4 KB lme4qtl : Linear mixed models with flexible covariance structure for genetic studies of related individuals / Ziyatdinov, Andrey (Chan School of Public Health) ; Vázquez-Santiago, Miquel (Hospital de la Santa Creu i Sant Pau (Barcelona, Catalunya)) ; Brunel, Helena (Hospital de la Santa Creu i Sant Pau (Barcelona, Catalunya)) ; Martinez-Perez, Angel (Institut d'Investigació Biomèdica Sant Pau) ; Aschard, Hugues (Biostatistique et Biologie Intégrative (C3BI)) ; Soria Fernández, José Manuel (Institut d'Investigació Biomèdica Sant Pau) ; Universitat Autònoma de Barcelona
Quantitative trait locus (QTL) mapping in genetic data often involves analysis of correlated observations, which need to be accounted for to avoid false association signals. This is commonly performed by modeling such correlations as random effects in linear mixed models (LMMs). [...]
2018 - 10.1186/s12859-018-2057-x
BMC bioinformatics, Vol. 19 Núm. 1 (27 2018) , p. 68  
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