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1.
13 p, 6.3 MB Validation of the new EPIC DNA methylation microarray (900K EPIC v2) for high-throughput profiling of the human DNA methylome / Noguera-Castells, Aleix (Institut Germans Trias i Pujol. Institut de Recerca contra la Leucèmia Josep Carreras) ; García-Prieto, Carlos A. (Institut Germans Trias i Pujol. Institut de Recerca contra la Leucèmia Josep Carreras) ; Álvarez-Errico, Damiana (Institut Germans Trias i Pujol. Institut de Recerca contra la Leucèmia Josep Carreras) ; Esteller, M (Institut Germans Trias i Pujol. Institut de Recerca contra la Leucèmia Josep Carreras)
DNA methylation, one of the best characterized epigenetic marks in the human genome, plays a pivotal role in gene transcription regulation and other biological processes in humans. On top of that, the DNA methylome undergoes profound changes in cancer and other disorders. [...]
2023 - 10.1080/15592294.2023.2185742
Epigenetics, Vol. 18 Núm. 1 (december 2023)  
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2.
6 p, 909.0 KB Analysis of the interplay between MeCP2 and histone H1 during in vitro differentiation of human ReNCell neural progenitor cells / Siqueira, E (Institut Germans Trias i Pujol. Institut de Recerca contra la Leucèmia Josep Carreras) ; Kim, Bo-Hyun (Department of Biochemistry and Microbiology. University of Victoria) ; Reser, Larry (Department of Chemistry. University of Virginia) ; Chow, Robert (Department of Biology. University of Victoria) ; Delaney, Kerry (Department of Biology. University of Victoria) ; Esteller, M (Universitat de Barcelona. Departament de Ciències Fisiològiques) ; Ross, Mark M. (Department of Chemistry. University of Virginia) ; Shabanowitz, Jeffrey (Department of Chemistry. University of Virginia) ; Hunt, Donald F. (Department of Pathology. University of Virginia) ; Guil, Sonia (Institut Germans Trias i Pujol. Institut de Recerca contra la Leucèmia Josep Carreras) ; Ausiö, Juan (Department of Biochemistry and Microbiology. University of Victoria)
An immortalized neural cell line derived from the human ventral mesencephalon, called ReNCell, and its MeCP2 knock out were used. With it, we characterized the chromatin compositional transitions undergone during differentiation, with special emphasis on linker histones. [...]
2023 - 10.1080/15592294.2023.2276425
Epigenetics, Vol. 18 Núm. 1 (2023) , p. 2276425  
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